| Literature DB >> 27781493 |
Domenico Tamburrino1, Stefano Partelli2, Claudio Renzi3, Stefano Crippa2, Francesca Muffatti2, Carolina Perali2, Amilcare Parisi4, Justus Randolph5, Giuseppe Kito Fusai1, Roberto Cirocchi3, Massimo Falconi2.
Abstract
INTRODUCTION: The safety of laparoscopic resections (LPS) of pancreatic neuroendocrine neoplasms (PNENs) has been well established in the literature. Areas covered: Studies conducted between January 2003 and December 2015 that reported on LPS and open surgery (OPS) were reviewed. The primary outcomes were the rate of post-operative complications and the length of hospital stay (LoS) after laparoscopic and open surgical resection. The rate of recurrence was the secondary outcome. Eleven studies were included with a total of 907 pancreatic resections for PNENs, of whom, 298 (32.8%) underwent LPS and 609 (67.2%) underwent open surgery. LPS resulted in a significantly shorter LoS (p < 0.0001) and lower blood loss (p < 0.0001). The meta-analysis did not show any significant difference in the pancreatic fistula rate, recurrence rate or post-operative mortality between the two groups. Expert commentary: LPS is a safe approach even for PNENs and it is associated with a shorter LoS.Entities:
Keywords: Pancreatic surgery; laparoscopic pancreatic resection; laparoscopy; minimally invasive surgery; neuroendocrine neoplasms
Mesh：
Year: 2016 PMID： 27781493 DOI： 10.1080/17474124.2017.1253473
Source DB: PubMed Journal: Expert Rev Gastroenterol Hepatol ISSN： 1747-4124 Impact factor: 3.869