| Literature DB >> 27781392 |
Michelle L Schoettler1, Dionne Graham2, Wen Tao3, Margaret Stack3, Elaine Shu3, Lauren Kerr2, Ellis J Neufeld1, Rachael F Grace1.
Abstract
An observational approach is recommended in newly diagnosed children with immune thrombocytopenia (ITP) at low risk of bleeding; however, there is no standard definition of risk. A standardized clinical assessment and management plan (SCAMP® ), a modifiable practice guideline, was implemented and revised (SCAMP-1 and SCAMP-2) and applied to 71 newly diagnosed patients with ITP. The Buchanan and Adix bleeding score guided treatment and was modified by stratifying by low- and high-risk grade 3 bleeding in SCAMP-2. Observation rates increased from 40% to 74% from SCAMP-1 to SCAMP-2 (P < 0.05) with no bleeding complications. We propose a modified bleeding score that increased observation rates in low-risk patients with ITP.Entities:
Keywords: bleeding; guideline; immune thrombocytopenia; pediatrics; treatment
Mesh:
Year: 2016 PMID: 27781392 PMCID: PMC5366076 DOI: 10.1002/pbc.26303
Source DB: PubMed Journal: Pediatr Blood Cancer ISSN: 1545-5009 Impact factor: 3.167