Literature DB >> 27780994

Glioblastoma Multiforme with Hemorrhage Mimicking an Aneurysm: Lessons Learnt.

Navneet Singla1, Ashish Aggarwal1, Sameer Vyas2, Ankur Sanghvi1, Pravin Salunke1, Ravi Garg1.   

Abstract

BACKGROUND: A sudden onset of neurological symptoms in patients is conventionally thought to be due to vascular phenomenon, with one common differential diagnosis being subarachnoid hemorrhage. Another important differential diagnosis is ischemic stroke. An uncommon cause of such acute symptoms can be hemorrhage in a pre-existing tumor, that is, intratumoral hemorrhage (ITH).
PURPOSE: ITH is an important, though uncommon differential diagnosis in cases of sudden onset of neurological deterioration. METHODS AND RESULT: A 60-year-old male presented with seizures and loss of consciousness 12 h prior to admission. The episode was sudden in onset. After detailed clinical and radiological investigations, the patient was diagnosed with glioma with bleed and was successfully operated upon.
CONCLUSION: The combination of hemorrhage and ischemic stroke pointed more towards an aneurysm rather than a tumor bleed. There were pointers both in favor of and against both the diagnosis. Therefore, a complex hemorrhagic cerebral tumor with acute presentation and discordant finding on CT or CT angiography should be characterized preoperatively. A large thrombosed aneurysm remains an important differential diagnosis.

Entities:  

Keywords:  Aneurysm; Glioblastoma; Intratumoral hemorrhage

Year:  2016        PMID: 27780994      PMCID: PMC5075732          DOI: 10.1159/000449488

Source DB:  PubMed          Journal:  Ann Neurosci        ISSN: 0972-7531


  3 in total

1.  MRI findings and pathological features in early-stage glioblastoma.

Authors:  Makoto Ideguchi; Koji Kajiwara; Hisaharu Goto; Kazutaka Sugimoto; Sadahiro Nomura; Eiji Ikeda; Michiyasu Suzuki
Journal:  J Neurooncol       Date:  2015-05-05       Impact factor: 4.130

2.  [Middle cerebral arterial occlusion secondary to brain tumor -- case report (author's transl)].

Authors:  H Kishikawa; K Iwatsuki; A Umeda
Journal:  No Shinkei Geka       Date:  1979-04

3.  Stroke in three patients due to spontaneous intra tumoral hemorrhage in meningiomas: Lessons learnt.

Authors:  Ashish Aggarwal; Kim Vaiphei; Amey R Savardekar; Pravin Salunke; Suresh N Mathuriya
Journal:  J Neurosci Rural Pract       Date:  2016 Jan-Mar
  3 in total
  1 in total

1.  Intracranial varix of the transverse-sigmoid dural arteriovenous fistula mimicking a ruptured middle cerebral artery aneurysm: A case report.

Authors:  Kuniyuki Onuma; Kiyoyuki Yanaka; Atsushi Tsukada; Kazuhiro Nakamura; Yuji Matsumaru; Eiichi Ishikawa
Journal:  Surg Neurol Int       Date:  2022-03-25
  1 in total

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