BACKGROUND: The objectives of this study were to examine the incidence and severity of early acute respiratory distress syndrome (ARDS) according to the Berlin Definition and to identify risk factors associated with the development of early post-traumatic ARDS. METHODS: A 2.5-year retrospective database of adult trauma patients who required mechanical ventilation for greater than 48 hours at a level 1 trauma center was analyzed for variables predictive of early (<48 hours after injury), mild, moderate, and severe ARDS and in-hospital mortality. RESULTS: Of 305 patients, 59 (19.3%) developed early ARDS: mild, 27 (45.8%); moderate, 26 (44.1%); and severe, 6 (10.1%). Performance of an emergent thoracotomy, blunt mechanism, and fresh frozen plasma administration were independently associated with the development of early ARDS. ARDS was not predictive of mortality. CONCLUSIONS: Trauma patients with blunt mechanism, who receive fresh frozen plasma, or undergo thoracotomy, are at risk of developing early ARDS. Copyright Â
BACKGROUND: The objectives of this study were to examine the incidence and severity of early acute respiratory distress syndrome (ARDS) according to the Berlin Definition and to identify risk factors associated with the development of early post-traumatic ARDS. METHODS: A 2.5-year retrospective database of adult traumapatients who required mechanical ventilation for greater than 48 hours at a level 1 trauma center was analyzed for variables predictive of early (<48 hours after injury), mild, moderate, and severe ARDS and in-hospital mortality. RESULTS: Of 305 patients, 59 (19.3%) developed early ARDS: mild, 27 (45.8%); moderate, 26 (44.1%); and severe, 6 (10.1%). Performance of an emergent thoracotomy, blunt mechanism, and fresh frozen plasma administration were independently associated with the development of early ARDS. ARDS was not predictive of mortality. CONCLUSIONS:Traumapatients with blunt mechanism, who receive fresh frozen plasma, or undergo thoracotomy, are at risk of developing early ARDS. Copyright Â
Authors: Elizabeth Y Killien; Brianna Mills; R Scott Watson; Monica S Vavilala; Frederick P Rivara Journal: Crit Care Med Date: 2018-12 Impact factor: 7.598
Authors: Elizabeth Y Killien; Brianna Mills; Monica S Vavilala; R Scott Watson; Grant E OʼKeefe; Frederick P Rivara Journal: J Trauma Acute Care Surg Date: 2019-05 Impact factor: 3.313
Authors: Julien Pottecher; Eric Noll; Marie Borel; Gérard Audibert; Sébastien Gette; Christian Meyer; Elisabeth Gaertner; Vincent Legros; Raphaël Carapito; Béatrice Uring-Lambert; Erik Sauleau; Walter G Land; Seiamak Bahram; Alain Meyer; Bernard Geny; Pierre Diemunsch Journal: Trials Date: 2020-03-18 Impact factor: 2.279