| Literature DB >> 27780064 |
Kristin Politi1, Serge Przedborski2.
Abstract
A recent study reports that microglia and oligodendrocytes promote motor neuron degeneration by inducing inflammation and necroptosis in a manner dependent on receptor-interacting kinase 1 (RIPK1). These findings could be significant for our understanding of the neurobiology and treatment of neurodegenerative diseases like amyotrophic lateral sclerosis.Entities:
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Year: 2016 PMID： 27780064 DOI： 10.1016/j.cub.2016.08.052
Source DB: PubMed Journal: Curr Biol ISSN： 0960-9822 Impact factor: 10.834