Literature DB >> 27778278

A Quantitative Mass-Spectrometry Platform to Monitor Changes in Cysteine Reactivity.

Yu Qian1, Eranthie Weerapana2.   

Abstract

Cysteine residues on proteins serve diverse functional roles in catalysis and regulation and are susceptible to numerous posttranslational modifications. Methods to monitor the reactivity of cysteines within the context of a complex proteome have facilitated the identification and functional characterization of cysteine residues on disparate proteins. Here, we describe the use of a cysteine-reactive iodoacetamide probe coupled to isotopically labeled, cleavable linkers to identify and quantify cysteine-reactivity changes from two biological samples.

Entities:  

Keywords:  Chemically cleavable azobenzene linker; Cu + click; Cysteine-reactivity; Iodoacetamide-alkyne; MudPIT; isoTOP-ABPP

Mesh：

Substances：

Year:  2017        PMID： 27778278      PMCID： PMC5359601          DOI： 10.1007/978-1-4939-6439-0_2

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  21 in total

1.  Tandem orthogonal proteolysis-activity-based protein profiling (TOP-ABPP)--a general method for mapping sites of probe modification in proteomes.

Authors:  Eranthie Weerapana; Anna E Speers; Benjamin F Cravatt
Journal:  Nat Protoc       Date:  2007       Impact factor: 13.491

2.  The biotin switch method for the detection of S-nitrosylated proteins.

Authors:  S R Jaffrey; S H Snyder
Journal:  Sci STKE       Date:  2001-06-12

Review 3.  Expanding the functional diversity of proteins through cysteine oxidation.

Authors:  Khalilah G Reddie; Kate S Carroll
Journal:  Curr Opin Chem Biol       Date:  2008-09-17       Impact factor: 8.822

Review 4.  Exploring protein lipidation with chemical biology.

Authors:  Howard C Hang; Maurine E Linder
Journal:  Chem Rev       Date:  2011-09-16       Impact factor: 60.622

Review 5.  Diverse functional roles of reactive cysteines.

Authors:  Nicholas J Pace; Eranthie Weerapana
Journal:  ACS Chem Biol       Date:  2012-11-29       Impact factor: 5.100

Review 6.  Chemical 'omics' approaches for understanding protein cysteine oxidation in biology.

Authors:  Stephen E Leonard; Kate S Carroll
Journal:  Curr Opin Chem Biol       Date:  2010-12-03       Impact factor: 8.822

Review 7.  Protein prenylation: molecular mechanisms and functional consequences.

Authors:  F L Zhang; P J Casey
Journal:  Annu Rev Biochem       Date:  1996       Impact factor: 23.643

8.  Proteome-wide quantification and characterization of oxidation-sensitive cysteines in pathogenic bacteria.

Authors:  Xin Deng; Eranthie Weerapana; Olesya Ulanovskaya; Fei Sun; Haihua Liang; Quanjiang Ji; Yan Ye; Ye Fu; Lu Zhou; Jiaxin Li; Haiyan Zhang; Chu Wang; Sophie Alvarez; Leslie M Hicks; Lefu Lan; Min Wu; Benjamin F Cravatt; Chuan He
Journal:  Cell Host Microbe       Date:  2013-03-13       Impact factor: 21.023

Review 9.  Fat chance! Getting a grip on a slippery modification.

Authors:  Christopher T M B Tom; Brent R Martin
Journal:  ACS Chem Biol       Date:  2012-12-18       Impact factor: 5.100

10.  A chemoproteomic platform to quantitatively map targets of lipid-derived electrophiles.

Authors:  Chu Wang; Eranthie Weerapana; Megan M Blewett; Benjamin F Cravatt
Journal:  Nat Methods       Date:  2013-12-01       Impact factor: 28.547
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  6 in total

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Authors:  Chi Zhang; Ekaterina V Vinogradova; Alexander M Spokoyny; Stephen L Buchwald; Bradley L Pentelute
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Review 2.  Reactive-cysteine profiling for drug discovery.

Authors:  Aaron J Maurais; Eranthie Weerapana
Journal:  Curr Opin Chem Biol       Date:  2019-03-18       Impact factor: 8.822

Review 3.  Redox Signaling by Reactive Electrophiles and Oxidants.

Authors:  Saba Parvez; Marcus J C Long; Jesse R Poganik; Yimon Aye
Journal:  Chem Rev       Date:  2018-08-27       Impact factor: 60.622

4.  Proteome-wide detection of S-nitrosylation targets and motifs using bioorthogonal cleavable-linker-based enrichment and switch technique.

Authors:  Ruzanna Mnatsakanyan; Stavroula Markoutsa; Kim Walbrunn; Andreas Roos; Steven H L Verhelst; René P Zahedi
Journal:  Nat Commun       Date:  2019-05-16       Impact factor: 14.919

5.  Pseudomonas aeruginosa Regulatory Protein AnvM Controls Pathogenicity in Anaerobic Environments and Impacts Host Defense.

Authors:  Yingchao Zhang; Chuan-Min Zhou; Qinqin Pu; Qun Wu; Shirui Tan; Xiaolong Shao; Weitong Zhang; Yingpeng Xie; Rongpeng Li; Xue-Jie Yu; Rui Wang; Liang Zhang; Min Wu; Xin Deng
Journal:  mBio       Date:  2019-07-23       Impact factor: 7.867

6.  Flavonoids in Ampelopsis grossedentata as covalent inhibitors of SARS-CoV-2 3CLpro: Inhibition potentials, covalent binding sites and inhibitory mechanisms.

Authors:  Yuan Xiong; Guang-Hao Zhu; Ya-Ni Zhang; Qing Hu; Hao-Nan Wang; Hao-Nan Yu; Xiao-Ya Qin; Xiao-Qing Guan; Yan-Wei Xiang; Hui Tang; Guang-Bo Ge
Journal:  Int J Biol Macromol       Date:  2021-07-29       Impact factor: 6.953
  6 in total

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