Literature DB >> 27778262

How do precision medicine and system biology response to human body's complex adaptability?

Bing Yuan1.   

Abstract

In the field of life sciences, although system biology and "precision medicine" introduce some complex scientifific methods and techniques, it is still based on the "analysis-reconstruction" of reductionist theory as a whole. Adaptability of complex system increase system behaviour uncertainty as well as the difficulties of precise identifification and control. It also put systems biology research into trouble. To grasp the behaviour and characteristics of organism fundamentally, systems biology has to abandon the "analysis-reconstruction" concept. In accordance with the guidelines of complexity science, systems biology should build organism model from holistic level, just like the Chinese medicine did in dealing with human body and disease. When we study the living body from the holistic level, we will fifind the adaptability of complex system is not the obstacle that increases the diffificulty of problem solving. It is the "exceptional", "right-hand man" that helping us to deal with the complexity of life more effectively.

Entities:  

Keywords:  adaptability; complexity science; personalized medicine; precision medicine; system biology

Mesh:

Year:  2016        PMID: 27778262     DOI: 10.1007/s11655-016-2605-z

Source DB:  PubMed          Journal:  Chin J Integr Med        ISSN: 1672-0415            Impact factor:   1.978


  1 in total

Review 1.  Precision medicine: Towards complexity science age.

Authors:  Bing Yuan
Journal:  Chin J Integr Med       Date:  2016-04-09       Impact factor: 1.978

  1 in total
  2 in total

Review 1.  Network Pharmacology in Research of Chinese Medicine Formula: Methodology, Application and Prospective.

Authors:  Ting-Ting Luo; Yuan Lu; Shi-Kai Yan; Xue Xiao; Xiang-Lu Rong; Jiao Guo
Journal:  Chin J Integr Med       Date:  2019-04-02       Impact factor: 1.978

Review 2.  Personalized or Precision Medicine? The Example of Cystic Fibrosis.

Authors:  Fernando A L Marson; Carmen S Bertuzzo; José D Ribeiro
Journal:  Front Pharmacol       Date:  2017-06-20       Impact factor: 5.810

  2 in total

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