Literature DB >> 27777519

Incidence, Predictors, and Impact of Postoperative Atrial Fibrillation after Coronary Artery Bypass Grafting in Military Veterans.

Shuab Omer, Lorraine D Cornwell, Ankur Bakshi, Eric Rachlin, Ourania Preventza, Todd K Rosengart, Joseph S Coselli, Scott A LeMaire, Nancy J Petersen, Greg Pattakos, Faisal G Bakaeen.   

Abstract

Little is known about the frequency and clinical implications of postoperative atrial fibrillation in military veterans who undergo coronary artery bypass grafting (CABG). We examined long-term survival data, clinical outcomes, and associated risk factors in this population. We retrospectively reviewed baseline, intraoperative, and postoperative data from 1,248 consecutive patients with similar baseline risk profiles who underwent primary isolated CABG at a Veterans Affairs hospital from October 2006 through March 2013. Multivariable logistic regression identified predictors of postoperative atrial fibrillation. Kaplan-Meier analysis was used to evaluate long-term survival (the primary outcome measure), morbidity, and length of hospital stay. Postoperative atrial fibrillation occurred in 215 patients (17.2%). Independent predictors of this sequela were age ≥65 years (odds ratios [95% confidence intervals], 1.7 [1.3-2.4] for patients of age 65-75 yr and 2.6 [1.4-4.8] for patients >75 yr) and body mass index ≥30 kg/m2 (2.0 [1.2-3.2]). Length of stay was longer for patients with postoperative atrial fibrillation than for those without (12.7 ± 6.6 vs 10.3 ± 8.9 d; P ≤0.0001), and the respective 30-day mortality rate was higher (1.9% vs 0.4%; P=0.014). Seven-year survival rates did not differ significantly. Older and obese patients are particularly at risk of postoperative atrial fibrillation after CABG. Patients who develop the sequela have longer hospital stays than, but similar long-term survival rates to, patients who do not.

Entities:  

Keywords:  Atrial fibrillation/epidemiology/etiology/mortality; coronary artery bypass/adverse effects; hospitals, veterans/statistics & numerical data; length of stay; postoperative complications; predictive value of tests; proportional hazards models; retrospective studies; risk assessment; treatment outcome

Mesh:

Year:  2016        PMID: 27777519      PMCID: PMC5067029          DOI: 10.14503/THIJ-15-5532

Source DB:  PubMed          Journal:  Tex Heart Inst J        ISSN: 0730-2347


  34 in total

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Authors:  M A Allessie; P A Boyden; A J Camm; A G Kléber; M J Lab; M J Legato; M R Rosen; P J Schwartz; P M Spooner; D R Van Wagoner ; A L Waldo
Journal:  Circulation       Date:  2001-02-06       Impact factor: 29.690

Review 2.  The renin-angiotensin system and natriuretic peptides in obesity-associated hypertension.

Authors:  S Engeli; A M Sharma
Journal:  J Mol Med (Berl)       Date:  2001       Impact factor: 4.599

3.  Rate-control versus conversion strategy in postoperative atrial fibrillation: a prospective, randomized pilot study.

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Journal:  Am Heart J       Date:  2000-12       Impact factor: 4.749

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Journal:  Circulation       Date:  1999-08-10       Impact factor: 29.690

5.  Atrial fibrillation independently prolongs hospital stay after coronary artery bypass surgery.

Authors:  J E Tamis; J S Steinberg
Journal:  Clin Cardiol       Date:  2000-03       Impact factor: 2.882

6.  Predictors, prevention, and long-term prognosis of atrial fibrillation after coronary artery bypass graft operations.

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Journal:  J Thorac Cardiovasc Surg       Date:  1987-09       Impact factor: 5.209

7.  Patients with postoperative atrial fibrillation have a doubled cardiovascular mortality.

Authors:  Anders Ahlsson; Lennart Bodin; Espen Fengsrud; Anders Englund
Journal:  Scand Cardiovasc J       Date:  2009       Impact factor: 1.589

8.  Hazards of postoperative atrial arrhythmias.

Authors:  L L Creswell; R B Schuessler; M Rosenbloom; J L Cox
Journal:  Ann Thorac Surg       Date:  1993-09       Impact factor: 4.330

9.  The impact of obesity on left ventricular mass and geometry. The Framingham Heart Study.

Authors:  M S Lauer; K M Anderson; W B Kannel; D Levy
Journal:  JAMA       Date:  1991-07-10       Impact factor: 56.272

10.  Influence of excess fat on cardiac morphology and function: study in uncomplicated obesity.

Authors:  Gianluca Iacobellis; Maria Cristina Ribaudo; Gaetano Leto; Alessandra Zappaterreno; Elio Vecci; Umberto Di Mario; Frida Leonetti
Journal:  Obes Res       Date:  2002-08
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  5 in total

1.  What Are the Predictors of Atrial Fibrillation in Coronary Artery Bypass Grafting?

Authors:  Orhan Gokalp; Levent Yilik; Hasan Iner; Gamze Gokalp
Journal:  Tex Heart Inst J       Date:  2017-02-01

2.  Circulating exosome-derived miR-122-5p is a novel biomarker for prediction of postoperative atrial fibrillation.

Authors:  Chen Bai; Yisi Liu; Yichen Zhao; Qing Ye; Cheng Zhao; Yang Liu; Jiangang Wang
Journal:  J Cardiovasc Transl Res       Date:  2022-05-05       Impact factor: 4.132

3.  [Elevation of C-reactive protein early after cardiopulmonary bypass surgery is associated with occurrence of postoperative atrial fibrillation].

Authors:  Y He; S Liu; Y Luo; H Wu; Y Yu; H Chen
Journal:  Nan Fang Yi Ke Da Xue Xue Bao       Date:  2022-03-20

4.  Postoperative atrial fibrillation in coronary artery bypass grafting herald poor outcome.

Authors:  Pulkit Malhotra; Shantanu Pande; Supaksh Mahindru; Ankit Thukral; Ankush Singh Kotwal; Rajan Prasad Gupta; Prabhat Tewari; Surendra Kumar Agarwal
Journal:  Ann Card Anaesth       Date:  2021 Oct-Dec

5.  Dose-response relationship among body mass index, abdominal adiposity and atrial fibrillation in patients undergoing cardiac surgery: a meta-analysis of 35 cohorts.

Authors:  Menglu Liu; Kaibo Mei; Lixia Xie; Jianyong Ma; Peng Yu; Siquan Niu; Ya Xu; Yujie Zhao; Xiao Liu
Journal:  PeerJ       Date:  2021-07-21       Impact factor: 2.984

  5 in total

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