| Literature DB >> 2777724 |
E Banfi1, M Cinco, S Perticarari, G Presani.
Abstract
The interactions between a strain of Borrelia burgdorferi and human polymorphonuclear leukocytes were studied by flow cytometry in the presence of specific or non-specific opsonizing factors. The capacity of the borrelias to stimulate leukocyte metabolism was also investigated. The results indicated that a low phagocytosis by isolated purified polymorphonuclear leukocytes did occur in the presence or absence of specific antibodies. Within whole blood the percentages of phagocytosting leukocytes increased in the presence of non-specific opsonizing factors. No stimulation of the oxidative metabolism stimulated by Borrelia was observed and PMA or zymosan stimulation of leukocytes was inhibited by the spirochaetes.Entities:
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Year: 1989 PMID： 2777724 DOI： 10.1111/j.1365-2672.1989.tb04952.x
Source DB: PubMed Journal: J Appl Bacteriol ISSN： 0021-8847