Literature DB >> 27776785

Has the rescheduling of hydrocodone changed ED prescribing practices?

Elizabeth C Oehler1, Rachel L Day2, David B Robinson3, Lawrence H Brown4.   

Abstract

OBJECTIVE: The objective was to examine the effect of hydrocodone-containing product (HCP) rescheduling on the proportion of prescriptions for HCPs given to patients discharged from the emergency department (ED).
METHODS: Electronic queries of ED records were used to identify patients aged 15 years and older discharged with a pain-related prescription in the 12 months before and after HCP rescheduling. Prescriptions were classified as HCPs; other Schedule II medications (eg, oxycodone products); other Schedule III medications (eg, codeine products); and non-Schedule II/III products (eg, nonsteroidal anti-inflammatory drugs). We compared the proportions of patients receiving each type of prescription before and after rescheduling using χ2 analysis and used logistic regression to explore the relationship between prescription type and time period while controlling for age, sex, race, and ethnicity.
RESULTS: Before rescheduling, 58.1% (95% confidence interval [CI], 57.4-58.7) of patients receiving a pain-related prescription received an HCP; after rescheduling, 13.2% (95% CI, 12.7-13.7) received an HCP (P < .001). Concurrently, other Schedule III prescriptions increased (pre: 11.7% [CI, 11.3-12.2] vs post: 44.9% [CI, 44.2-45.6], P < .001)), as did non-Schedule II/III prescriptions (pre: 51.8% [CI, 51.2-52.5] vs post: 59.3% [CI, 58.6-60.0], P < .001). When controlling for demographic characteristics, patients remained less likely to receive an HCP after rescheduling (adjusted odds ratio [AOR], 0.11; CI, 0.10-0.11) and more likely to receive other Schedule III (AOR, 6.1; CI, 5.8-6.5) and non-Schedule II/III (AOR, 1.4; CI, 1.3-1.4) products.
CONCLUSION: Rescheduling HCPs from Schedule III to Schedule II led to a substantial decrease in HCP prescriptions in our ED and an increase in prescriptions for other Schedule III and non-Schedule II/III products.
Copyright © 2016 Elsevier Inc. All rights reserved.

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Year:  2016        PMID: 27776785     DOI: 10.1016/j.ajem.2016.09.002

Source DB:  PubMed          Journal:  Am J Emerg Med        ISSN: 0735-6757            Impact factor:   2.469


  8 in total

1.  Opioid Prescriptions in Older Medicare Beneficiaries After the 2014 Federal Rescheduling of Hydrocodone Products.

Authors:  Yong-Fang Kuo; Mukaila A Raji; Victor Liaw; Jacques Baillargeon; James S Goodwin
Journal:  J Am Geriatr Soc       Date:  2018-04-14       Impact factor: 5.562

2.  Decline in opioid prescribing after federal rescheduling of hydrocodone products.

Authors:  Mukaila A Raji; Yong-Fang Kuo; Deepak Adhikari; Jacques Baillargeon; James S Goodwin
Journal:  Pharmacoepidemiol Drug Saf       Date:  2017-12-21       Impact factor: 2.890

3.  Opioid Prescribing Trends in Women Following Mastectomy or Breast-Conserving Surgery Before and After the 2014 Federal Reclassification of Hydrocodone.

Authors:  Derrick C Gibson; Lin-Na Chou; Mukaila A Raji; Jacques G Baillargeon; Yong-Fang Kuo
Journal:  Oncologist       Date:  2019-12-04

4.  Quantification of Opioid Prescription Practice Changes Due to Hydrocodone Combination Product Rescheduling in an Academic Pain Clinic.

Authors:  John Ngo; David Parker; Mathew Meroney; Jasmine Mitchell; Oscar Veloz; Oliver Lee; Katherine A Cunningham; Denise Wilkes
Journal:  J Pain Res       Date:  2020-08-25       Impact factor: 3.133

5.  Opioid Prescribing Trends in Women Following Mastectomy or Breast-Conserving Surgery Before and After the 2014 Federal Reclassification of Hydrocodone.

Authors:  Derrick C Gibson; Lin-Na Chou; Mukaila A Raji; Jacques G Baillargeon; Yong-Fang Kuo
Journal:  Oncologist       Date:  2019-12-08

6.  Effects of Rescheduling Hydrocodone on Opioid Prescribing in Ohio.

Authors:  Yingna Liu; Olesya Baker; Jeremiah D Schuur; Scott G Weiner
Journal:  Pain Med       Date:  2020-09-01       Impact factor: 3.750

Review 7.  Tramadol Prescription over a 4-Year Period in the USA.

Authors:  Luisa M Bigal; Kristen Bibeau; Stephanie Dunbar
Journal:  Curr Pain Headache Rep       Date:  2019-08-06

8.  Effect of restricting the legal supply of prescription opioids on buying through online illicit marketplaces: interrupted time series analysis.

Authors:  James Martin; Jack Cunliffe; David Décary-Hétu; Judith Aldridge
Journal:  BMJ       Date:  2018-06-13
  8 in total

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