| Literature DB >> 27776781 |
X Liu1, S Yang1, C-W Yu2, C-Y Chen2, K Wu3.
Abstract
Reversible histone acetylation and deacetylation at the N-terminus of histone tails play a crucial role in regulation of gene activity. Hyperacetylation of histones relaxes chromatin structure and is associated with transcriptional activation, whereas hypoacetylation of histones induces chromatin compaction and gene repression. Histone acetylation and deacetylation are catalyzed by histone acetyltransferases (HATs) and histone deacetylases (HDACs), respectively. Emerging evidences revealed that plant HATs and HDACs play essential roles in regulation of gene expression in plant development and plant responses to environmental stresses. Furthermore, HATs and HDACs were shown to interact with various chromatin-remodeling factors and transcription factors involved in transcriptional regulation of multiple developmental processes.Keywords: Histone acetylation; Histone acetyltransferases; Histone deacetylases; Plant development
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Year: 2016 PMID： 27776781 DOI： 10.1016/bs.enz.2016.08.001
Source DB: PubMed Journal: Enzymes ISSN： 1874-6047