Erin M Warshaw1, Solveig L Hagen, Denis Sasseville, Howard I Maibach, Joel G DeKoven, Donald V Belsito, Joseph F Fowler, Kathryn A Zug, James S Taylor, C G Toby Mathias, Anthony F Fransway, Vincent A DeLeo, James G Marks, Melanie D Pratt, Matthew J Zirwas, Frances J Storrs. 1. From the *HCMC Parkside Occupational and Contact Dermatitis Clinic and Department of Dermatology, Minneapolis Veterans Affairs Medical Center; †Department of Dermatology, University of Minnesota Medical School, Minneapolis; ‡Division of Dermatology, Royal Victoria Hospital, McGill University, Montreal, Quebec, Canada; §Department of Dermatology, University of California San Francisco; ∥Division of Dermatology, Sunnybrook Health Sciences Centre, University of Toronto, Ontario, Canada; ¶Department of Dermatology, Columbia University, New York, NY; #University of Louisville, KY; **Dartmouth-Hitchcock Medical Center, Lebanon, NH; ††Department of Dermatology, Cleveland Clinic; ‡‡Department of Dermatology, University of Cincinnati, OH; §§Associates in Dermatology, Fort Myers, FL; ∥∥University of Southern California, Keck School of Medicine, Los Angeles; ¶¶Department of Dermatology, Pennsylvania State University, University Park; ##Division of Dermatology, University of Ottawa, Canada; ***Ohio State University, Columbus; and †††Department of Dermatology, Oregon Health Science University, Portland.
Abstract
BACKGROUND: Contact dermatoses are common in mechanic and repair occupations. OBJECTIVES: This study aimed to (1) estimate the prevalence of occupationally related contact dermatitis among mechanics/repairers patch tested from 1998 to 2014 by the North American Contact Dermatitis Group, (2) characterize responsible allergens and irritants, and their sources, and (3) compare results among 3 occupational subgroups (mechanics, electrical/electronic, and other). METHODS: A cross-sectional analysis of patients patch tested by the North American Contact Dermatitis Group between 1998 and 2014. RESULTS: Of 38,784 patients patch tested, 691 (1.8%) were mechanics/repairers. Male sex (93.5%) and hand involvement (59.5%) were common overall. Occupationally related skin disease was more prevalent among vehicle and mobile equipment mechanics/repairers (52.7%) and other mechanics/repairers (41.4%) than electrical/electronic equipment mechanics/repairers (21.3%). Overall, carba mix, thiuram mix, and methylchloroisothiazolone/methylisothiazolone were the most common occupation-related clinically relevant allergens. Gloves, automotive vehicles, solvents, oils, lubricants, and fuels were the most common sources of responsible allergens. CONCLUSIONS: Common occupationally related allergens included rubber accelerators and the preservative methylchloroisothiazolone/methylisothiazolone.
BACKGROUND: Contact dermatoses are common in mechanic and repair occupations. OBJECTIVES: This study aimed to (1) estimate the prevalence of occupationally related contact dermatitis among mechanics/repairers patch tested from 1998 to 2014 by the North American Contact Dermatitis Group, (2) characterize responsible allergens and irritants, and their sources, and (3) compare results among 3 occupational subgroups (mechanics, electrical/electronic, and other). METHODS: A cross-sectional analysis of patients patch tested by the North American Contact Dermatitis Group between 1998 and 2014. RESULTS: Of 38,784 patients patch tested, 691 (1.8%) were mechanics/repairers. Male sex (93.5%) and hand involvement (59.5%) were common overall. Occupationally related skin disease was more prevalent among vehicle and mobile equipment mechanics/repairers (52.7%) and other mechanics/repairers (41.4%) than electrical/electronic equipment mechanics/repairers (21.3%). Overall, carba mix, thiuram mix, and methylchloroisothiazolone/methylisothiazolone were the most common occupation-related clinically relevant allergens. Gloves, automotive vehicles, solvents, oils, lubricants, and fuels were the most common sources of responsible allergens. CONCLUSIONS: Common occupationally related allergens included rubber accelerators and the preservative methylchloroisothiazolone/methylisothiazolone.
Authors: Anna Tagka; George I Lambrou; George K Matsopoulos; Despoina Fytili; Daphne Mirkopoulou; Alexandra Katsarou; Argyro Chatziioannou; Alexandros Stratigos Journal: Biomed Res Int Date: 2021-05-06 Impact factor: 3.411