Literature DB >> 27775789

Roles of PECAM-1 in cell function and disease progression.

Y-M Feng1, X-H Chen, X Zhang.   

Abstract

Platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31) belongs to immunoglobulin superfamily, which is key factor for adhesion and accumulation of platelets. It is proved that PECAM-1 is closely correlative with cell migration, proliferation, apoptosis, signal transduction and cellular immunity. Meanwhile, PECAM-1 involves in multiple clinical diseases, such as atherosclerosis, thrombosis and leukemia. This paper reviewed the structure and function of PECAM-1, and its roles in cell function and disease generation and progression.

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Year:  2016        PMID: 27775789

Source DB:  PubMed          Journal:  Eur Rev Med Pharmacol Sci        ISSN: 1128-3602            Impact factor:   3.507


  12 in total

1.  Serum CXCL13 and PECAM-1 can be used as diagnostic and prognostic markers in elderly patients with gastric cancer.

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3.  Traditional Chinese Medicine ShenZhuGuanXin Granules Mitigate Cardiac Dysfunction and Promote Myocardium Angiogenesis in Myocardial Infarction Rats by Upregulating PECAM-1/CD31 and VEGF Expression.

Authors:  Dan-Ping Xu; De-Zhi Zou; Hui-Liang Qiu; Huan-Lin Wu
Journal:  Evid Based Complement Alternat Med       Date:  2017-07-03       Impact factor: 2.629

4.  Detailed resolution analysis reveals spatial T cell heterogeneity in the invasive margin of colorectal cancer liver metastases associated with improved survival.

Authors:  Anna Berthel; Inka Zoernig; Nektarios A Valous; Christoph Kahlert; Fee Klupp; Alexis Ulrich; Juergen Weitz; Dirk Jaeger; Niels Halama
Journal:  Oncoimmunology       Date:  2017-02-23       Impact factor: 8.110

Review 5.  Platelet Endothelial Cell Adhesion Molecule-1 and Oligodendrogenesis: Significance in Alcohol Use Disorders.

Authors:  Chitra D Mandyam; Emmanuel G Villalpando; Noah L Steiner; Leon W Quach; McKenzie J Fannon; Sucharita S Somkuwar
Journal:  Brain Sci       Date:  2017-10-16

6.  Characterisation of tumour microvessel density during progression of high-grade serous ovarian cancer: clinico-pathological impact (an OCTIPS Consortium study).

Authors:  Ilary Ruscito; Dan Cacsire Castillo-Tong; Ignace Vergote; Iulia Ignat; Mandy Stanske; Adriaan Vanderstichele; Jacek Glajzer; Hagen Kulbe; Fabian Trillsch; Alexander Mustea; Caroline Kreuzinger; Pierluigi Benedetti Panici; Charlie Gourley; Hani Gabra; Marianna Nuti; Eliane T Taube; Mirjana Kessler; Jalid Sehouli; Silvia Darb-Esfahani; Elena Ioana Braicu
Journal:  Br J Cancer       Date:  2018-06-29       Impact factor: 7.640

Review 7.  Endothelial dysfunction in neuroprogressive disorders-causes and suggested treatments.

Authors:  Gerwyn Morris; Basant K Puri; Lisa Olive; Andre Carvalho; Michael Berk; Ken Walder; Lise Tuset Gustad; Michael Maes
Journal:  BMC Med       Date:  2020-10-19       Impact factor: 8.775

8.  SIRT1-induced deacetylation of Akt expedites platelet phagocytosis and delays HEMEC aging.

Authors:  Yong Lan; Min Dong; Yongjun Li; Yongpeng Diao; Zuoguang Chen; Yangfang Li
Journal:  Mol Ther Nucleic Acids       Date:  2021-01-26       Impact factor: 8.886

9.  Association of PECAM-1 Gene Polymorphisms with Kawasaki Disease in Chinese Children.

Authors:  Zhuoying Li; Dong Han; Jie Jiang; Jia Chen; Lang Tian; Zuocheng Yang
Journal:  Dis Markers       Date:  2017-04-23       Impact factor: 3.434

10.  Metformin reverses the drug resistance of cisplatin in irradiated CNE-1 human nasopharyngeal carcinoma cells through PECAM-1 mediated MRPs down-regulation.

Authors:  Yingming Sun; Xiaochuan Chen; Yajuan Zhou; Sufang Qiu; Yongyang Wu; Min Xie; Guofang Zhu; Shanshan Liang; Heming Li; Dong Zhou; Zaishuang Ju; Fuguang Wang; Fang Han; Zhe Wang; Ruoyu Wang
Journal:  Int J Med Sci       Date:  2020-09-01       Impact factor: 3.738

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