Emmi Helle1,2,3, Sture Andersson1, Unto Häkkinen3, Jutta Järvelin4, Janne Eskelinen5, Eero Kajantie1,6,7. 1. Children's Hospital, Helsinki University Hospital and University of Helsinki, Helsinki, Finland. 2. Stanford University School of Medicine, Cardiovascular Medicine, Stanford, CA. 3. Centre for Health and Social Economics, National Institute for Health and Welfare, Helsinki, Finland. 4. Information Services, National Institute for Health and Welfare, Helsinki, Finland. 5. Statistics Finland, Helsinki, Finland. 6. Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland. 7. Department of Obstetrics and Gynecology, MRC Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland.
Abstract
BACKGROUND: Early term birth is associated with increased need for hospital care during the early postnatal period. The objective of this study was to assess the morbidity and health care-related costs during the first 3 years of life in children born early term. METHODS: Data come from a population-based birth cohort study in the municipalities of Helsinki, Espoo, and Vantaa, Finland using data from the national medical birth register and outpatient, inpatient, and primary care registers. All surviving infants born in 2006-08 (n = 29 970) were included. The main outcome measures were morbidities, based on ICD-10 codes recorded during inpatient and outpatient hospital visits, and health care costs, based on all care received, including well child visits (specialised care, primary care, private care, and medications). RESULTS: 7.0% of children born full term had at least one of the studied morbidities by 3 years of age. This percentage was significantly higher in children born early term: 8.6% (adjusted odds ratio 1.2, 95% confidence interval (CI) 1.1, 1.4). The increased morbidity of children born early term was attributed to obstructive airway diseases and ophthalmological and motor problems. Health care-related costs during the first 3 years of life were 4813€ (95% CI 4385, 5241) per child in the early term group, higher than for full term children 4047€ (95% CI 3884, 4210). CONCLUSIONS: Infants born early term have increased morbidity and higher health care-related costs during early childhood than full term infants. Early term birth seems to be associated with a health disadvantage.
BACKGROUND: Early term birth is associated with increased need for hospital care during the early postnatal period. The objective of this study was to assess the morbidity and health care-related costs during the first 3 years of life in children born early term. METHODS: Data come from a population-based birth cohort study in the municipalities of Helsinki, Espoo, and Vantaa, Finland using data from the national medical birth register and outpatient, inpatient, and primary care registers. All surviving infants born in 2006-08 (n = 29 970) were included. The main outcome measures were morbidities, based on ICD-10 codes recorded during inpatient and outpatient hospital visits, and health care costs, based on all care received, including well child visits (specialised care, primary care, private care, and medications). RESULTS: 7.0% of children born full term had at least one of the studied morbidities by 3 years of age. This percentage was significantly higher in children born early term: 8.6% (adjusted odds ratio 1.2, 95% confidence interval (CI) 1.1, 1.4). The increased morbidity of children born early term was attributed to obstructive airway diseases and ophthalmological and motor problems. Health care-related costs during the first 3 years of life were 4813€ (95% CI 4385, 5241) per child in the early term group, higher than for full term children 4047€ (95% CI 3884, 4210). CONCLUSIONS:Infants born early term have increased morbidity and higher health care-related costs during early childhood than full term infants. Early term birth seems to be associated with a health disadvantage.
Authors: Kara M Rood; Catalin S Buhimschi; Theresa Dible; Shaylyn Webster; Guomao Zhao; Philip Samuels; Irina A Buhimschi Journal: EClinicalMedicine Date: 2019-03-01
Authors: Juhi K Gupta; Angharad Care; Laura Goodfellow; Zarko Alfirevic; Lu-Yun Lian; Bertram Müller-Myhsok; Ana Alfirevic; Marie M Phelan Journal: Biosci Rep Date: 2021-09-30 Impact factor: 3.840
Authors: Salma Younes; Muthanna Samara; Rana Al-Jurf; Gheyath Nasrallah; Sawsan Al-Obaidly; Husam Salama; Tawa Olukade; Sara Hammuda; Mohamed A Ismail; Ghassan Abdoh; Palli Valapila Abdulrouf; Thomas Farrell; Mai AlQubaisi; Hilal Al Rifai; Nader Al-Dewik Journal: Int J Environ Res Public Health Date: 2021-05-29 Impact factor: 3.390