Literature DB >> 2777421

Single-dose pharmacokinetics of flurbiprofen granules and tablets in healthy volunteers.

C Benvenuti1, V Gambaro, F Lodi, C Scaroni, G Bandi, M Valenti.   

Abstract

The bioavailability of granules and tablet flurbiprofen in 100 mg single dose was crossover compared in 6 healthy volunteers (mean aged 26.8 years). The granules showed an earlier peaktime and a lower maximum concentration than the tablet. Area under the curve and half-time in terminal phase were similar, with the granule relative bioavailability of 0.98.

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Year:  1989        PMID: 2777421

Source DB:  PubMed          Journal:  Int J Clin Pharmacol Ther Toxicol        ISSN: 0174-4879


  3 in total

1.  Evaluation of flurbiprofen urinary ratios as in vivo indices for CYP2C9 activity.

Authors:  N K Zgheib; R F Frye; T S Tracy; M Romkes; R A Branch
Journal:  Br J Clin Pharmacol       Date:  2006-10-19       Impact factor: 4.335

Review 2.  Clinical pharmacokinetics of flurbiprofen and its enantiomers.

Authors:  N M Davies
Journal:  Clin Pharmacokinet       Date:  1995-02       Impact factor: 6.447

3.  Clinical study on the bioequivalence of two tablet formulations of flurbiprofen.

Authors:  Latif Ozbay; Durisehvar Ozer Unal; Iclal Cakici; Aysen Fenercioglu; Dilek Erol
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2009 Jan-Mar       Impact factor: 2.441

  3 in total

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