Literature DB >> 27773928

E3 ubiquitin ligase Cbl-b activates the p53 pathway by targeting Siva1, a negative regulator of ARF, in FLT3 inhibitor-resistant acute myeloid leukemia.

I-K Park1,2, W Blum3, S D Baker1,2, M A Caligiuri1,3.   

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Year:  2016        PMID： 27773928      PMCID： PMC5509909          DOI： 10.1038/leu.2016.293

Source DB:  PubMed          Journal:  Leukemia        ISSN： 0887-6924            Impact factor:   11.528


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  16 in total

1.  SIRT1 prevents genotoxic stress-induced p53 activation in acute myeloid leukemia.

Authors:  Daniel Sasca; Patricia S Hähnel; Jakub Szybinski; Kaml Khawaja; Oliver Kriege; Saskia V Pante; Lars Bullinger; Susanne Strand; Dennis Strand; Matthias Theobald; Thomas Kindler
Journal:  Blood       Date:  2014-05-22       Impact factor: 22.113

2.  The p53 Target Gene SIVA Enables Non-Small Cell Lung Cancer Development.

Authors:  Jeanine L Van Nostrand; Alice Brisac; Stephano S Mello; Suzanne B R Jacobs; Richard Luong; Laura D Attardi
Journal:  Cancer Discov       Date:  2015-03-26       Impact factor: 39.397

3.  c-Cbl and Cbl-b ligases mediate 17-allylaminodemethoxygeldanamycin-induced degradation of autophosphorylated Flt3 kinase with internal tandem duplication through the ubiquitin proteasome pathway.

Authors:  Gaku Oshikawa; Toshikage Nagao; Nan Wu; Tetsuya Kurosu; Osamu Miura
Journal:  J Biol Chem       Date:  2011-07-18       Impact factor: 5.157

4.  Modeling the therapeutic efficacy of p53 restoration in tumors.

Authors:  Carla P Martins; Lamorna Brown-Swigart; Gerard I Evan
Journal:  Cell       Date:  2006-12-21       Impact factor: 41.582

5.  Reactivating the ARF-p53 axis in AML cells by targeting ULF.

Authors:  Delin Chen; Jong-Bok Yoon; Wei Gu
Journal:  Cell Cycle       Date:  2010-08-11       Impact factor: 4.534

6.  Mll partial tandem duplication and Flt3 internal tandem duplication in a double knock-in mouse recapitulates features of counterpart human acute myeloid leukemias.

Authors:  Nicholas A Zorko; Kelsie M Bernot; Susan P Whitman; Ronald F Siebenaler; Elshafa H Ahmed; Gabriele G Marcucci; Daniel A Yanes; Kathleen K McConnell; Charlene Mao; Chidimma Kalu; Xiaoli Zhang; David Jarjoura; Adrienne M Dorrance; Nyla A Heerema; Benjamin H Lee; Gang Huang; Guido Marcucci; Michael A Caligiuri
Journal:  Blood       Date:  2012-06-06       Impact factor: 22.113

Review 7.  Awakening guardian angels: drugging the p53 pathway.

Authors:  Christopher J Brown; Sonia Lain; Chandra S Verma; Alan R Fersht; David P Lane
Journal:  Nat Rev Cancer       Date:  2009-12       Impact factor: 60.716

8.  Siva1 inhibits p53 function by acting as an ARF E3 ubiquitin ligase.

Authors:  Xingwu Wang; Meng Zha; Xiaocheng Zhao; Peng Jiang; Wenjing Du; Andrew Y H Tam; Yide Mei; Mian Wu
Journal:  Nat Commun       Date:  2013       Impact factor: 14.919

Review 9.  FLT3 inhibition and mechanisms of drug resistance in mutant FLT3-positive AML.

Authors:  Ellen Weisberg; Rosemary Barrett; Qingsong Liu; Richard Stone; Nathanael Gray; James D Griffin
Journal:  Drug Resist Updat       Date:  2009-05-20       Impact factor: 18.500

10.  SIRT1 activation by a c-MYC oncogenic network promotes the maintenance and drug resistance of human FLT3-ITD acute myeloid leukemia stem cells.

Authors:  Ling Li; Tereza Osdal; Yinwei Ho; Sookhee Chun; Tinisha McDonald; Puneet Agarwal; Allen Lin; Su Chu; Jing Qi; Liang Li; Yao-Te Hsieh; Cedric Dos Santos; Hongfeng Yuan; Trung-Quang Ha; Mihaela Popa; Randi Hovland; Øystein Bruserud; Bjørn Tore Gjertsen; Ya-Huei Kuo; Wenyong Chen; Sonia Lain; Emmet McCormack; Ravi Bhatia
Journal:  Cell Stem Cell       Date:  2014-10-02       Impact factor: 24.633
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  8 in total

1.  The role of E3 ubiquitin ligase WWP2 and the regulation of PARP1 by ubiquitinated degradation in acute lymphoblastic leukemia.

Authors:  Xinxin Lu; Xinyue Huang; Haiqi Xu; Saien Lu; Shilong You; Jiaqi Xu; Qianru Zhan; Chao Dong; Ning Zhang; Ying Zhang; Liu Cao; Xingang Zhang; Naijin Zhang; Lijun Zhang
Journal:  Cell Death Discov       Date:  2022-10-18

2.  Transcriptome-Wide Analysis of RNA N6-Methyladenosine Modification in Adriamycin-Resistant Acute Myeloid Leukemia Cells.

Authors:  Shu Fang; Bo Peng; Yanan Wen; Jingjing Yang; Hao Wang; Ziwei Wang; Kun Qian; Yan Wei; Yifan Jiao; Chunji Gao; Liping Dou
Journal:  Front Genet       Date:  2022-04-28       Impact factor: 4.772

3.  Bacterial CagA protein compromises tumor suppressor mechanisms in gastric epithelial cells.

Authors:  Manikandan Palrasu; Elena Zaika; Wael El-Rifai; Monica Garcia-Buitrago; Maria Blanca Piazuelo; Keith T Wilson; Richard M Peek; Alexander I Zaika
Journal:  J Clin Invest       Date:  2020-05-01       Impact factor: 19.456

Review 4.  Essential Roles of E3 Ubiquitin Ligases in p53 Regulation.

Authors:  Sanam Sane; Khosrow Rezvani
Journal:  Int J Mol Sci       Date:  2017-02-17       Impact factor: 5.923

Review 5.  Siva-1 emerges as a tissue-specific oncogene beyond its classic role of a proapoptotic gene.

Authors:  Jiri Vachtenheim; Robert Lischke; Jiri Vachtenheim
Journal:  Onco Targets Ther       Date:  2018-10-01       Impact factor: 4.147

6.  MicroRNA-29b-2-5p inhibits cell proliferation by directly targeting Cbl-b in pancreatic ductal adenocarcinoma.

Authors:  Ce Li; Qian Dong; Xiaofang Che; Ling Xu; Zhi Li; Yibo Fan; Kezuo Hou; Shuo Wang; Jinglei Qu; Lu Xu; Ti Wen; Xianghong Yang; Xiujuan Qu; Yunpeng Liu
Journal:  BMC Cancer       Date:  2018-06-25       Impact factor: 4.430

7.  Clinical resistance to crenolanib in acute myeloid leukemia due to diverse molecular mechanisms.

Authors:  Haijiao Zhang; Samantha Savage; Anna Reister Schultz; Daniel Bottomly; Libbey White; Erik Segerdell; Beth Wilmot; Shannon K McWeeney; Christopher A Eide; Tamilla Nechiporuk; Amy Carlos; Rachel Henson; Chenwei Lin; Robert Searles; Hoang Ho; Yee Ling Lam; Richard Sweat; Courtney Follit; Vinay Jain; Evan Lind; Gautam Borthakur; Guillermo Garcia-Manero; Farhad Ravandi; Hagop M Kantarjian; Jorge Cortes; Robert Collins; Daelynn R Buelow; Sharyn D Baker; Brian J Druker; Jeffrey W Tyner
Journal:  Nat Commun       Date:  2019-01-16       Impact factor: 17.694

Review 8.  Acute Myeloid Leukemia-Related Proteins Modified by Ubiquitin and Ubiquitin-like Proteins.

Authors:  Sang-Soo Park; Kwang-Hyun Baek
Journal:  Int J Mol Sci       Date:  2022-01-03       Impact factor: 5.923
  8 in total

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