| Literature DB >> 27773678 |
Jeffrey M Pyne1, Joseph I Constans2, Mark D Wiederhold3, Douglas P Gibson4, Timothy Kimbrell5, Teresa L Kramer6, Jeffery A Pitcock7, Xiaotong Han8, D Keith Williams9, Don Chartrand10, Richard N Gevirtz11, James Spira12, Brenda K Wiederhold3, Rollin McCraty13, Thomas R McCune4.
Abstract
Heart rate variability is a physiological measure associated with autonomic nervous system activity. This study hypothesized that lower pre-deployment HRV would be associated with higher post-deployment post-traumatic stress disorder (PTSD) symptoms. Three-hundred-forty-three Army National Guard soldiers enrolled in the Warriors Achieving Resilience (WAR) study were analyzed. The primary outcome was PTSD symptom severity using the PTSD Checklist - Military version (PCL) measured at baseline, 3- and 12-month post-deployment. Heart rate variability predictor variables included: high frequency power (HF) and standard deviation of the normal cardiac inter-beat interval (SDNN). Generalized linear mixed models revealed that the pre-deployment PCL*ln(HF) interaction term was significant (p<0.0001). Pre-deployment SDNN was not a significant predictor of post-deployment PCL. Covariates included age, pre-deployment PCL, race/ethnicity, marital status, tobacco use, childhood abuse, pre-deployment traumatic brain injury, and previous combat zone deployment. Pre-deployment heart rate variability predicts post-deployment PTSD symptoms in the context of higher pre-deployment PCL scores. Published by Elsevier B.V.Entities:
Keywords: Post-traumatic stress disorder (PTSD); combat stress; heart rate variability; longitudinal; military; prediction; risk factors
Mesh：
Year: 2016 PMID： 27773678 PMCID： PMC5335901 DOI： 10.1016/j.biopsycho.2016.10.008
Source DB: PubMed Journal: Biol Psychol ISSN： 0301-0511 Impact factor: 3.251