Literature DB >> 2777329

Histochemical studies on the distribution of certain dehydrogenases in squamous cell carcinoma of cheek.

S Banerjee, D K Bhatt.   

Abstract

Histochemical distribution of lactate, isocitrate and succinate dehydrogenases in normal oral epithelium and in well differentiated squamous cell carcinoma of cheek region was studied. Lactate dehydrogenase, isocitrate dehydrogenase, and succinate dehydrogenase activity was found to be more in the malignant cells. Succinate and lactate dehydrogenase presented a conspicuous pattern in which the cells located at the periphery of the malignant sheets in well differentiated squamous cell carcinoma showed moderate to intense activity as compared to cells in the central portion. The results are discussed and it is suggested that the enhanced glycolysis and subdued function of the tricarboxylic acid cycle is not a universal criterion during malignancy as reported in the previous investigations.

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Year:  1989        PMID： 2777329

Source DB:  PubMed          Journal:  Indian J Cancer        ISSN： 0019-509X            Impact factor:   1.224


  10 in total

1.  In vivo multiphoton microscopy of NADH and FAD redox states, fluorescence lifetimes, and cellular morphology in precancerous epithelia.

Authors:  Melissa C Skala; Kristin M Riching; Annette Gendron-Fitzpatrick; Jens Eickhoff; Kevin W Eliceiri; John G White; Nirmala Ramanujam
Journal:  Proc Natl Acad Sci U S A       Date:  2007-11-27       Impact factor: 11.205

2.  Optically sectioned wide-field fluorescence lifetime imaging microscopy enabled by structured illumination.

Authors:  Taylor Hinsdale; Cory Olsovsky; Jose J Rico-Jimenez; Kristen C Maitland; Javier A Jo; Bilal H Malik
Journal:  Biomed Opt Express       Date:  2017-02-08       Impact factor: 3.732

3.  Real-time histology in liver disease using multiphoton microscopy with fluorescence lifetime imaging.

Authors:  Haolu Wang; Xiaowen Liang; Yousuf H Mohammed; James A Thomas; Kim R Bridle; Camilla A Thorling; Jeffrey E Grice; Zhi Ping Xu; Xin Liu; Darrell H G Crawford; Michael S Roberts
Journal:  Biomed Opt Express       Date:  2015-02-10       Impact factor: 3.732

4.  In vivo multiphoton fluorescence lifetime imaging of protein-bound and free nicotinamide adenine dinucleotide in normal and precancerous epithelia.

Authors:  Melissa C Skala; Kristin M Riching; Damian K Bird; Annette Gendron-Fitzpatrick; Jens Eickhoff; Kevin W Eliceiri; Patricia J Keely; Nirmala Ramanujam
Journal:  J Biomed Opt       Date:  2007 Mar-Apr       Impact factor: 3.170

5.  Phasor fluorescence lifetime microscopy of free and protein-bound NADH reveals neural stem cell differentiation potential.

Authors:  Chiara Stringari; Jamison L Nourse; Lisa A Flanagan; Enrico Gratton
Journal:  PLoS One       Date:  2012-11-05       Impact factor: 3.240

6.  Metabolic trajectory of cellular differentiation in small intestine by Phasor Fluorescence Lifetime Microscopy of NADH.

Authors:  Chiara Stringari; Robert A Edwards; Kira T Pate; Marian L Waterman; Peter J Donovan; Enrico Gratton
Journal:  Sci Rep       Date:  2012-08-10       Impact factor: 4.379

7.  Probing metabolic states of differentiating stem cells using two-photon FLIM.

Authors:  Aleksandra V Meleshina; Varvara V Dudenkova; Marina V Shirmanova; Vladislav I Shcheslavskiy; Wolfgang Becker; Alena S Bystrova; Elena I Cherkasova; Elena V Zagaynova
Journal:  Sci Rep       Date:  2016-02-25       Impact factor: 4.379

8.  Chemotherapy with cisplatin: insights into intracellular pH and metabolic landscape of cancer cells in vitro and in vivo.

Authors:  Marina V Shirmanova; Irina N Druzhkova; Maria M Lukina; Varvara V Dudenkova; Nadezhda I Ignatova; Ludmila B Snopova; Vladislav I Shcheslavskiy; Vsevolod V Belousov; Elena V Zagaynova
Journal:  Sci Rep       Date:  2017-08-21       Impact factor: 4.379

9.  Optical metabolic imaging of treatment response in human head and neck squamous cell carcinoma.

Authors:  Amy T Shah; Michelle Demory Beckler; Alex J Walsh; William P Jones; Paula R Pohlmann; Melissa C Skala
Journal:  PLoS One       Date:  2014-03-04       Impact factor: 3.240

10.  Comparison of Salivary and Serum Alkaline Phosphates Level and Lactate Dehydrogenase Levels in Patients with Tobacco Related Oral Lesions with Healthy Subjects - A Step Towards Early Diagnosis.

Authors:  Gaurav Goyal
Journal:  Asian Pac J Cancer Prev       Date:  2020-04-01
  10 in total

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