Literature DB >> 27771936

Auraptene and Its Role in Chronic Diseases.

Giuseppe Derosa1,2,3,4, Pamela Maffioli5,6,7, Amirhossein Sahebkar8,9,10.   

Abstract

Auraptene (7-geranyloxycoumarin) is the best known and most abundant prenyloxycoumarin present in nature. It is synthesized by various plant species, mainly those of the Rutaceae and Umbeliferae (Apiaceae) families, comprising many edible fruits and vegetables such as lemons, grapefruit and orange. Auraptene has shown a remarkable effect in the prevention of degenerative diseases, in particular it has been reported to be one the most promising known natural chemopreventive agents against several types of cancer. The aim of this chapter is to review the effects of auraptene in the prevention and treatment of different chronic diseases.

Entities:  

Keywords:  Auraptene; Chemoprevention; Degenerative diseases; Hypertension; Lipid profile

Mesh：

Substances：

Year:  2016        PMID： 27771936     DOI： 10.1007/978-3-319-41342-6_19

Source DB:  PubMed          Journal:  Adv Exp Med Biol        ISSN： 0065-2598            Impact factor:   2.622


  6 in total

1.  Auraptene ameliorates osteoporosis by inhibiting RANKL/NFATc1 pathway-mediated bone resorption based on network pharmacology and experimental evaluation.

Authors:  Mi H Kim; La Y Choi; Jae Y Chung; Eun-Jung Kim; Woong M Yang
Journal:  Bone Joint Res       Date:  2022-05       Impact factor: 4.410

2.  Combination of auraptene and arsenic trioxide induces apoptosis and cellular accumulation in the subG1 phase in adult T-cell leukemia cells.

Authors:  Mohaddeseh Kazemi; Hamideh Kouhpeikar; Zahra Delbari; Faeze Khodadadi; Sina Gerayli; Mehrdad Iranshahi; Arman Mosavat; Fatemeh Behnam Rassouli; Houshang Rafatpanah
Journal:  Iran J Basic Med Sci       Date:  2021-12       Impact factor: 2.699

3.  Semisynthesis of Selenoauraptene.

Authors:  Serena Fiorito; Francesco Epifano; Lorenzo Marchetti; Salvatore Genovese
Journal:  Molecules       Date:  2021-05-10       Impact factor: 4.411

4.  The Coumarin Derivative 5'-Hydroxy Auraptene Suppresses Osteoclast Differentiation via Inhibiting MAPK and c-Fos/NFATc1 Pathways.

Authors:  Basem M Abdallah; Enas M Ali; Hany Elsawy; Gehan M Badr; Ashraf M Abdel-Moneim; Abdullah M Alzahrani
Journal:  Biomed Res Int       Date:  2019-12-28       Impact factor: 3.411

5.  Citrus Auraptene Induces Glial Cell Line-Derived Neurotrophic Factor in C6 Cells.

Authors:  Yoshiko Furukawa; Ryu-Ichi Hara; Makiko Nakaya; Satoshi Okuyama; Atsushi Sawamoto; Mitsunari Nakajima
Journal:  Int J Mol Sci       Date:  2019-12-30       Impact factor: 5.923

6.  Suppression of Human Platelet Activation via Integrin αIIbβ3 Outside-In Independent Signal and Reduction of the Mortality in Pulmonary Thrombosis by Auraptene.

Authors:  Chih-Wei Hsia; Cheng-Lin Tsai; Joen-Rong Sheu; Wan-Jung Lu; Chih-Hsuan Hsia; Marappan Velusamy; Thanasekaran Jayakumar; Jiun-Yi Li
Journal:  Int J Mol Sci       Date:  2019-11-08       Impact factor: 5.923
  6 in total

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