| Literature DB >> 27771384 |
Amy B Hahn1, Maryanne Mackey2, Don Constantino2, Ashar Ata3, Nikolaos Chandolias4, Reynold Lopez-Soler4, David J Conti4.
Abstract
The new UNOS kidney allocation system awards very high points to candidates with cPRA 99% and 100%, and allows for national sharing for cPRA 100% candidates. We sought to determine the effect of this new kidney allocation system on candidates who are very highly sensitized (90-98% cPRA) but not eligible for very high points or national sharing by examining offers to these candidates for 5months pre-implementation and two consecutive 5month periods post-implementation and comparing them to cPRA⩾99% candidates. We found that the cPRA⩾99% candidates received significantly more offers and transplants after implementation, while offers and transplants to the 90-98% candidates decreased. A slight adjustment to the allocation system may be needed to provide more equitable distribution of kidneys to all high cPRA candidates.Entities:
Keywords: Allocation; Antibody; Kidney; Renal; Transplant
Mesh:
Substances:
Year: 2016 PMID: 27771384 DOI: 10.1016/j.humimm.2016.10.010
Source DB: PubMed Journal: Hum Immunol ISSN: 0198-8859 Impact factor: 2.850