| Literature DB >> 27770256 |
Megan O'Reilly1, Bernard Thébaud2,3.
Abstract
Preterm birth occurs in approximately 11 % of all births worldwide. Advances in perinatal care have enabled the survival of preterm infants born as early as 23-24 weeks of gestation. However, many are affected by bronchopulmonary dysplasia (BPD)-a common respiratory complication of preterm birth, which has life-long consequences for lung health. Currently, there is no specific treatment for BPD. Recent advances in stem cell research have opened new therapeutic avenues for prevention/repair of lung damage. This review summarizes recent pre-clinical data and early clinical translation of cell-based therapies for BPD.Entities:
Keywords: Bronchopulmonary dysplasia; Lung injury; Mesenchymal stem cell; Preterm; Regeneration
Mesh:
Year: 2016 PMID: 27770256 DOI: 10.1007/s00441-016-2517-4
Source DB: PubMed Journal: Cell Tissue Res ISSN: 0302-766X Impact factor: 5.249