Literature DB >> 27770256

Cell-based therapies for neonatal lung disease.

Megan O'Reilly1, Bernard Thébaud2,3.   

Abstract

Preterm birth occurs in approximately 11 % of all births worldwide. Advances in perinatal care have enabled the survival of preterm infants born as early as 23-24 weeks of gestation. However, many are affected by bronchopulmonary dysplasia (BPD)-a common respiratory complication of preterm birth, which has life-long consequences for lung health. Currently, there is no specific treatment for BPD. Recent advances in stem cell research have opened new therapeutic avenues for prevention/repair of lung damage. This review summarizes recent pre-clinical data and early clinical translation of cell-based therapies for BPD.

Entities:  

Keywords:  Bronchopulmonary dysplasia; Lung injury; Mesenchymal stem cell; Preterm; Regeneration

Mesh:

Year:  2016        PMID: 27770256     DOI: 10.1007/s00441-016-2517-4

Source DB:  PubMed          Journal:  Cell Tissue Res        ISSN: 0302-766X            Impact factor:   5.249


  8 in total

1.  Extracellular Vesicle Transfer from Mesenchymal Stromal Cells Modulates Macrophage Function in Acute Lung Injury. Basic Science and Clinical Implications.

Authors:  Michael A Matthay
Journal:  Am J Respir Crit Care Med       Date:  2017-11-15       Impact factor: 21.405

2.  Human induced pluripotent stem cells ameliorate hyperoxia-induced lung injury in a mouse model.

Authors:  Adam Mitchell; Heather Wanczyk; Todd Jensen; Christine Finck
Journal:  Am J Transl Res       Date:  2020-01-15       Impact factor: 4.060

Review 3.  Preventing bronchopulmonary dysplasia: new tools for an old challenge.

Authors:  María Álvarez-Fuente; Laura Moreno; Jane A Mitchell; Irwin K Reiss; Paloma Lopez; Dolores Elorza; Liesbeth Duijts; Alejandro Avila-Alvarez; Luis Arruza; Manuel Ramirez Orellana; Eugenio Baraldi; Patrizia Zaramella; Santiago Rueda; Álvaro Gimeno-Díaz de Atauri; Hercília Guimarães; Gustavo Rocha; Elisa Proença; Bernard Thébaud; Maria Jesús Del Cerro
Journal:  Pediatr Res       Date:  2018-11-21       Impact factor: 3.756

Review 4.  The Future of Bronchopulmonary Dysplasia: Emerging Pathophysiological Concepts and Potential New Avenues of Treatment.

Authors:  Jennifer J P Collins; Dick Tibboel; Ismé M de Kleer; Irwin K M Reiss; Robbert J Rottier
Journal:  Front Med (Lausanne)       Date:  2017-05-22

5.  Two-year outcomes of infants enrolled in the first-in-human study of amnion cells for bronchopulmonary dysplasia.

Authors:  Atul Malhotra; Rebecca Lim; Joanne C Mockler; Euan M Wallace
Journal:  Stem Cells Transl Med       Date:  2019-11-27       Impact factor: 6.940

6.  First-In-Human Administration of Allogeneic Amnion Cells in Premature Infants With Bronchopulmonary Dysplasia: A Safety Study.

Authors:  Rebecca Lim; Atul Malhotra; Jean Tan; Siow Teng Chan; Sinnee Lau; Dandan Zhu; Joanne C Mockler; Euan M Wallace
Journal:  Stem Cells Transl Med       Date:  2018-08-05       Impact factor: 6.940

7.  Oxygen and mechanical ventilation impede the functional properties of resident lung mesenchymal stromal cells.

Authors:  Alvaro G Moreira; Sartaj K Siddiqui; Rolando Macias; Teresa L Johnson-Pais; Desiree Wilson; Jonathon A L Gelfond; Margarita M Vasquez; Steven R Seidner; Shamimunisa B Mustafa
Journal:  PLoS One       Date:  2020-03-06       Impact factor: 3.240

Review 8.  Mesenchymal Stromal Cells for the Treatment of Interstitial Lung Disease in Children: A Look from Pediatric and Pediatric Surgeon Viewpoints.

Authors:  Gloria Pelizzo; Serena Silvestro; Maria Antonietta Avanzini; Gianvincenzo Zuccotti; Emanuela Mazzon; Valeria Calcaterra
Journal:  Cells       Date:  2021-11-23       Impact factor: 6.600

  8 in total

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