Literature DB >> 27770227

Prevalence of comorbidities and management of gout in a tropical city in Australia.

Andrew Jeyaruban1,2, Muriel Soden3, Sarah Larkins4.   

Abstract

To examine the management of gout in general practice in Townsville, Australia, and to explore comorbid conditions in patients with gout. Study will also explore how closely guidelines are being followed in managing gout. Retrospective chart review was conducted from May to November 2014 in three general practices in Townsville. Registers for patients were established by searching "gout" and "gouty arthritis". Three hundred and twenty-one patients were included in the study after excluding inactive patients, patients below age of 18 and patients with cancer. Main outcome measures were prevalence of comorbidities in gout patients, gout medications and adequate serum urate control (≤0.36 mmol/l). Multivariate logistic regression was used to study the relationship between serum urate level, comorbid conditions and lifestyle factors. Hypertension was the most common comorbid condition with 60.8 % of patients followed by obesity and dyslipidaemia. In terms of medication, 46.7 % of patients were on allopurinol, 12.8 % on indomethacin and 13.4 % on diuretics. Eighty-six percentage of patients had serum urate level (sUA) recorded in the previous year. Of these, 32.2 % had a serum urate level below or equal to 0.36 mmol/l. Moreover, 17.4 % of patients had lifestyle advice documented in chart. Male gender was the most influential factor in having poor uric acid control (p < 0.01), followed by not being on allopurinol (p < 0.01) and patients older than 50 years (p = 0.02). Management of gout in this study sample was not entirely concordant with guidelines. The study also suggests a need for possible tighter monitoring and allopurinol dosing regime in older, male patients.

Entities:  

Keywords:  Allopurinol; Family medicine; General practice; Gout; Gouty arthritis

Mesh:

Substances:

Year:  2016        PMID: 27770227     DOI: 10.1007/s00296-016-3580-6

Source DB:  PubMed          Journal:  Rheumatol Int        ISSN: 0172-8172            Impact factor:   2.631


  17 in total

Review 1.  Systematic review of the prevalence of gout and hyperuricaemia in Australia.

Authors:  P C Robinson; W J Taylor; T R Merriman
Journal:  Intern Med J       Date:  2012-04-04       Impact factor: 2.048

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Authors:  Hyon K Choi; David B Mount; Anthony M Reginato
Journal:  Ann Intern Med       Date:  2005-10-04       Impact factor: 25.391

Review 3.  Management of gout in general practice--a systematic review.

Authors:  Andrew Jeyaruban; Sarah Larkins; Muriel Soden
Journal:  Clin Rheumatol       Date:  2014-09-17       Impact factor: 2.980

4.  Sex differences in gout epidemiology: evaluation and treatment.

Authors:  L R Harrold; R A Yood; T R Mikuls; S E Andrade; J Davis; J Fuller; K A Chan; D Roblin; M A Raebel; A Von Worley; R Platt; K G Saag
Journal:  Ann Rheum Dis       Date:  2006-04-27       Impact factor: 19.103

Review 5.  EULAR evidence based recommendations for gout. Part II: Management. Report of a task force of the EULAR Standing Committee for International Clinical Studies Including Therapeutics (ESCISIT).

Authors:  W Zhang; M Doherty; T Bardin; E Pascual; V Barskova; P Conaghan; J Gerster; J Jacobs; B Leeb; F Lioté; G McCarthy; P Netter; G Nuki; F Perez-Ruiz; A Pignone; J Pimentão; L Punzi; E Roddy; T Uhlig; I Zimmermann-Gòrska
Journal:  Ann Rheum Dis       Date:  2006-05-17       Impact factor: 19.103

6.  Prescription and comorbidity screening following consultation for acute gout in primary care.

Authors:  Edward Roddy; Christian D Mallen; Samantha L Hider; Kelvin P Jordan
Journal:  Rheumatology (Oxford)       Date:  2009-11-17       Impact factor: 7.580

Review 7.  Update on gout: new therapeutic strategies and options.

Authors:  Robert Terkeltaub
Journal:  Nat Rev Rheumatol       Date:  2010-01       Impact factor: 20.543

8.  Concordance of the management of chronic gout in a UK primary-care population with the EULAR gout recommendations.

Authors:  Edward Roddy; Weiya Zhang; Michael Doherty
Journal:  Ann Rheum Dis       Date:  2007-05-15       Impact factor: 19.103

9.  Gout in the UK and Germany: prevalence, comorbidities and management in general practice 2000-2005.

Authors:  L Annemans; E Spaepen; M Gaskin; M Bonnemaire; V Malier; T Gilbert; G Nuki
Journal:  Ann Rheum Dis       Date:  2007-11-02       Impact factor: 19.103

10.  Improvement in the management of gout is vital and overdue: an audit from a UK primary care medical practice.

Authors:  Elizabeth Cottrell; Valerie Crabtree; John J Edwards; Edward Roddy
Journal:  BMC Fam Pract       Date:  2013-11-14       Impact factor: 2.497

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  3 in total

1.  Prevalence of Hypertension in Sudanese Patients With Gouty Arthritis.

Authors:  Sufian M Khaild; Amro M Fagir; Ziryab I Taha; Awadelkareem A Elshareef; Mohammed H Mohammed; Khalda M Saeed; Elnour M Elagib; Elwalied M Ibrahim; Jimmy William
Journal:  Cureus       Date:  2022-04-18

2.  What factors contribute to uncontrolled gout and hospital admission? A qualitative study of inpatients and their primary care practitioners.

Authors:  Darren Chyi Hsiang Kong; Elizabeth Ann Sturgiss; Annamma Kochummen Dorai Raj; Kieran Fallon
Journal:  BMJ Open       Date:  2019-12-23       Impact factor: 2.692

3.  Gout prevalence and predictors of urate-lowering therapy use: results from a population-based study.

Authors:  Huai Leng Pisaniello; Susan Lester; David Gonzalez-Chica; Nigel Stocks; Marie Longo; Greg R Sharplin; Eleonora Dal Grande; Tiffany K Gill; Samuel L Whittle; Catherine L Hill
Journal:  Arthritis Res Ther       Date:  2018-07-11       Impact factor: 5.156

  3 in total

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