Literature DB >> 27769978

Rare case of type I hypersensitivity reaction to sodium hypochlorite solution in a healthcare setting.

Gabriel Chia Shi Zhe1, Andrew Green2, Yuke Tien Fong3, Haur Yueh Lee1, Sweet Far Ho4.   

Abstract

Sodium hypochlorite is a clear yellowish solution with a characteristic odour of chlorine and is commonly used as a disinfectant and a bleaching agent. It is used in various healthcare settings for its fast-acting and broad-spectrum antimicrobial activity. It is a known irritant and there are some reports that it can also cause allergic contact dermatitis of type IV hypersensitivity. We report a case of work-related type I hypersensitivity to sodium hypochlorite, presenting with recurrent urticarial rash and a positive prick test reaction to this chemical. He was subsequently excused from further exposure with no further recurrences of the urticarial rash. To the best of our knowledge, this is the first such reported case due to work in the healthcare setting. 2016 BMJ Publishing Group Ltd.

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Year:  2016        PMID: 27769978      PMCID: PMC5093827          DOI: 10.1136/bcr-2016-217228

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  7 in total

1.  Contact allergy to sodium hypochlorite in Eusol.

Authors:  S K Ng; C L Goh
Journal:  Contact Dermatitis       Date:  1989-10       Impact factor: 6.600

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Journal:  Contact Dermatitis       Date:  1977-10       Impact factor: 6.600

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Authors:  W A Rutala; D J Weber
Journal:  Clin Microbiol Rev       Date:  1997-10       Impact factor: 26.132

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Authors:  J M Habets; A M Geursen-Reitsma; E Stolz; T van Joost
Journal:  Contact Dermatitis       Date:  1986-09       Impact factor: 6.600

5.  Allergy to sodium hypochlorite during root canal therapy: a case report.

Authors:  M K Calişkan; M Türkün; S Alper
Journal:  Int Endod J       Date:  1994-05       Impact factor: 5.264

6.  Irritation factors of sodium hypochlorite solutions in human skin.

Authors:  J J Hostynek; K P Wilhelm; A B Cua; H I Maibach
Journal:  Contact Dermatitis       Date:  1990-11       Impact factor: 6.600

7.  The skin prick test - European standards.

Authors:  Lucie Heinzerling; Adriano Mari; Karl-Christian Bergmann; Megon Bresciani; Guido Burbach; Ulf Darsow; Stephen Durham; Wytske Fokkens; Mark Gjomarkaj; Tari Haahtela; Ana Todo Bom; Stefan Wöhrl; Howard Maibach; Richard Lockey
Journal:  Clin Transl Allergy       Date:  2013-02-01       Impact factor: 5.871

  7 in total
  3 in total

1.  Health effects of sodium hypochlorite: review of published case reports.

Authors:  Insung Chung; Hyeseung Ryu; Seong-Yong Yoon; Jea Chul Ha
Journal:  Environ Anal Health Toxicol       Date:  2022-03-30

Review 2.  Hypochlorous Acid: From Innate Immune Factor and Environmental Toxicant to Chemopreventive Agent Targeting Solar UV-Induced Skin Cancer.

Authors:  Jeremy A Snell; Jana Jandova; Georg T Wondrak
Journal:  Front Oncol       Date:  2022-04-29       Impact factor: 5.738

Review 3.  Wound Antiseptics and European Guidelines for Antiseptic Application in Wound Treatment.

Authors:  Zuzanna Łucja Babalska; Marzena Korbecka-Paczkowska; Tomasz M Karpiński
Journal:  Pharmaceuticals (Basel)       Date:  2021-12-02
  3 in total

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