Eli Kisilevsky1, Luminita Tarita-Nistor2, Esther G González3, Mark S Mandelcorn4, Michael H Brent4, Samuel N Markowitz4, Martin J Steinbach3. 1. Vision Science Research Program, Toronto Western Hospital, Toronto, Ont.; Faculty of Medicine, University of Toronto, Toronto, Ont.. Electronic address: eli.kisilevsky@mail.utoronto.ca. 2. Vision Science Research Program, Toronto Western Hospital, Toronto, Ont. 3. Vision Science Research Program, Toronto Western Hospital, Toronto, Ont.; Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ont.; Centre for Vision Research, York University, Toronto, Ont. 4. Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ont.
Abstract
OBJECTIVE: Patients with central vision loss develop preferred retinal loci (PRLs) in the eccentric retina. The characteristics of the PRLs for the better eye (BE) are well studied, but not those of the worse eye (WE). We examined the distribution of monocular PRLs in the visual field (VF), as well as visual acuity, fixation stability, and PRL eccentricity for the BE and WE of patients with central vision loss. DESIGN: Retrospective consecutive case series. PARTICIPANTS: A total of 87 BE and 50 WE of patients with central vision loss. METHODS: Visual acuity, fixation stability, PRL location, and PRL eccentricity measures were retrieved from our database. PRL location was categorized into 5 VF segments: central, superior, inferior, left, and right. RESULTS: For BE, PRL frequency distribution was significantly different for the 5 VF segments, χ2(4) = 19.9, p = 0.001. Most PRLs occurred in inferior (31%) and left (31%) VF segments. Visual acuity, fixation stability, and PRL eccentricity depended on the VF segment. Visual acuity correlated with fixation stability and PRL eccentricity. For WE, PRL frequency distribution was not different for the 5 VF segments and visual acuity was not dependent on the VF segment. No relationships between visual acuity and PRL eccentricity or fixation stability were found. CONCLUSIONS: Different patterns of PRL characteristics were found for BEs and for WEs. These findings are important to consider when factors such as PRL eccentricity, visual acuity, fixation stability, and PRL location are used as outcome measures after treatment or rehabilitation and when monitoring disease progression.
OBJECTIVE:Patients with central vision loss develop preferred retinal loci (PRLs) in the eccentric retina. The characteristics of the PRLs for the better eye (BE) are well studied, but not those of the worse eye (WE). We examined the distribution of monocular PRLs in the visual field (VF), as well as visual acuity, fixation stability, and PRL eccentricity for the BE and WE of patients with central vision loss. DESIGN: Retrospective consecutive case series. PARTICIPANTS: A total of 87 BE and 50 WE of patients with central vision loss. METHODS: Visual acuity, fixation stability, PRL location, and PRL eccentricity measures were retrieved from our database. PRL location was categorized into 5 VF segments: central, superior, inferior, left, and right. RESULTS: For BE, PRL frequency distribution was significantly different for the 5 VF segments, χ2(4) = 19.9, p = 0.001. Most PRLs occurred in inferior (31%) and left (31%) VF segments. Visual acuity, fixation stability, and PRL eccentricity depended on the VF segment. Visual acuity correlated with fixation stability and PRL eccentricity. For WE, PRL frequency distribution was not different for the 5 VF segments and visual acuity was not dependent on the VF segment. No relationships between visual acuity and PRL eccentricity or fixation stability were found. CONCLUSIONS: Different patterns of PRL characteristics were found for BEs and for WEs. These findings are important to consider when factors such as PRL eccentricity, visual acuity, fixation stability, and PRL location are used as outcome measures after treatment or rehabilitation and when monitoring disease progression.
Authors: Irina Sverdlichenko; Mark S Mandelcorn; Galia Issashar Leibovitzh; Efrem D Mandelcorn; Samuel N Markowitz; Luminita Tarita-Nistor Journal: Ophthalmic Physiol Opt Date: 2021-12-04 Impact factor: 3.992
Authors: Luminita Tarita-Nistor; Mark S Mandelcorn; Efrem D Mandelcorn; Samuel N Markowitz Journal: Transl Vis Sci Technol Date: 2020-07-30 Impact factor: 3.283