Literature DB >> 27767094

Warm feelings for TRPM2.

Thomas Voets1.   

Abstract

Two recent studies reveal a crucial role for the cation channel TRPM2 in sensing warm temperatures, both in the thermoregulatory center of the brain and in the somatosensory system.

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Year:  2016        PMID： 27767094      PMCID： PMC5099870          DOI： 10.1038/cr.2016.121

Source DB:  PubMed          Journal:  Cell Res        ISSN： 1001-0602            Impact factor:   25.617


  10 in total

1.  Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia.

Authors:  J B Davis; J Gray; M J Gunthorpe; J P Hatcher; P T Davey; P Overend; M H Harries; J Latcham; C Clapham; K Atkinson; S A Hughes; K Rance; E Grau; A J Harper; P L Pugh; D C Rogers; S Bingham; A Randall; S A Sheardown
Journal:  Nature       Date:  2000-05-11       Impact factor: 49.962

Review 2.  TRPM2.

Authors:  Malika Faouzi; Reinhold Penner
Journal:  Handb Exp Pharmacol       Date:  2014

Review 3.  Peripheral thermosensation in mammals.

Authors:  Joris Vriens; Bernd Nilius; Thomas Voets
Journal:  Nat Rev Neurosci       Date:  2014-07-23       Impact factor: 34.870

Review 4.  Still cooling after all these years: Meta-analysis of pre-clinical trials of therapeutic hypothermia for acute ischemic stroke.

Authors:  Oana M Dumitrascu; Jessica Lamb; Patrick D Lyden
Journal:  J Cereb Blood Flow Metab       Date:  2016-04-18       Impact factor: 6.200

5.  TRPM3 is a nociceptor channel involved in the detection of noxious heat.

Authors:  Joris Vriens; Grzegorz Owsianik; Thomas Hofmann; Stephan E Philipp; Julia Stab; Xiaodi Chen; Melissa Benoit; Fenqin Xue; Annelies Janssens; Sara Kerselaers; Johannes Oberwinkler; Rudi Vennekens; Thomas Gudermann; Bernd Nilius; Thomas Voets
Journal:  Neuron       Date:  2011-05-12       Impact factor: 17.173

6.  TRPM2 activation by cyclic ADP-ribose at body temperature is involved in insulin secretion.

Authors:  Kazuya Togashi; Yuji Hara; Tomoko Tominaga; Tomohiro Higashi; Yasunobu Konishi; Yasuo Mori; Makoto Tominaga
Journal:  EMBO J       Date:  2006-04-06       Impact factor: 11.598

7.  Impaired nociception and pain sensation in mice lacking the capsaicin receptor.

Authors:  M J Caterina; A Leffler; A B Malmberg; W J Martin; J Trafton; K R Petersen-Zeitz; M Koltzenburg; A I Basbaum; D Julius
Journal:  Science       Date:  2000-04-14       Impact factor: 47.728

8.  Impaired thermosensation in mice lacking TRPV3, a heat and camphor sensor in the skin.

Authors:  Aziz Moqrich; Sun Wook Hwang; Taryn J Earley; Matt J Petrus; Amber N Murray; Kathryn S R Spencer; Mary Andahazy; Gina M Story; Ardem Patapoutian
Journal:  Science       Date:  2005-03-04       Impact factor: 47.728

9.  The TRPM2 ion channel is required for sensitivity to warmth.

Authors:  Chun-Hsiang Tan; Peter A McNaughton
Journal:  Nature       Date:  2016-08-17       Impact factor: 49.962

10.  The TRPM2 channel is a hypothalamic heat sensor that limits fever and can drive hypothermia.

Authors:  Kun Song; Hong Wang; Gretel B Kamm; Jörg Pohle; Fernanda de Castro Reis; Paul Heppenstall; Hagen Wende; Jan Siemens
Journal:  Science       Date:  2016-08-25       Impact factor: 47.728
  10 in total
  1 in total

Review 1.  Cellular populations and thermosensing mechanisms of the hypothalamic thermoregulatory center.

Authors:  Jan Siemens; Gretel B Kamm
Journal:  Pflugers Arch       Date:  2018-01-27       Impact factor: 3.657
  1 in total

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