| Literature DB >> 2776653 |
M Oimomi1, T Nakamichi, T Ohara, M Sakai, N Igaki, F Hata, S Baba.
Abstract
We investigated in vitro the effect of the polyol pathway on the formation of advanced Maillard reaction products which have fluorescence and cross-links. Bovine serum albumin supplemented with various concentrations of glucose, fructose or sorbitol was incubated for 14 days. The fluorescence intensity was higher after incubation with fructose than after incubation with glucose. However, no significant increase in fluorescence intensity was found after incubation with sorbitol. These results suggest that in the polyol pathway fructose plays an important role in the formation of advanced Maillard products.Entities:
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Year: 1989 PMID: 2776653 DOI: 10.1016/0168-8227(89)90104-6
Source DB: PubMed Journal: Diabetes Res Clin Pract ISSN: 0168-8227 Impact factor: 5.602