Literature DB >> 27766278

A metastatic castration resistant prostate cancer patient with multiple bone metastases has durable biochemical and radiological response to docetaxel chemotherapy.

Tatsuaki Daimon1, Takeo Kosaka1, Mototsugu Oya1.   

Abstract

Docetaxel chemotherapy for metastatic castration resistant prostate cancer patients has been thought palliative because the radiological response rate is low and durable response is rare. The patient was a 64-year-old man who was diagnosed with cT3aN0M0 prostate cancer and underwent external beam radiation therapy as the initial treatment. He underwent androgen deprivation therapy and 8 cycles of docetaxel chemotherapy. His PSA level decreased and became undetectable and the disease was confirmed to be stable by radiological examination. We report a rare case that a metastatic castration resistant prostate cancer patient with multiple bone metastases has durable radiological and biochemical response.

Entities:  

Keywords:  Docetaxel; metastatic castration resistant prostate cancer; multiple bone metastasis; prostatic neoplasms

Year:  2016        PMID: 27766278      PMCID: PMC5069273     

Source DB:  PubMed          Journal:  Am J Clin Exp Urol        ISSN: 2330-1910


  5 in total

Review 1.  PSA surge/flare-up in patients with castration-refractory prostate cancer during the initial phase of chemotherapy.

Authors:  T Nelius; S Filleur
Journal:  Prostate       Date:  2009-12-01       Impact factor: 4.104

Review 2.  Transient therapy-related surge in serum tumor biomarkers: characterizing behavior and postulating its biologic role.

Authors:  Suneel D Mundle; Anuj S Marathe; Mohan Chelladurai
Journal:  Crit Rev Oncol Hematol       Date:  2012-10-04       Impact factor: 6.312

3.  Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer.

Authors:  Ian F Tannock; Ronald de Wit; William R Berry; Jozsef Horti; Anna Pluzanska; Kim N Chi; Stephane Oudard; Christine Théodore; Nicholas D James; Ingela Turesson; Mark A Rosenthal; Mario A Eisenberger
Journal:  N Engl J Med       Date:  2004-10-07       Impact factor: 91.245

4.  Design and end points of clinical trials for patients with progressive prostate cancer and castrate levels of testosterone: recommendations of the Prostate Cancer Clinical Trials Working Group.

Authors:  Howard I Scher; Susan Halabi; Ian Tannock; Michael Morris; Cora N Sternberg; Michael A Carducci; Mario A Eisenberger; Celestia Higano; Glenn J Bubley; Robert Dreicer; Daniel Petrylak; Philip Kantoff; Ethan Basch; William Kevin Kelly; William D Figg; Eric J Small; Tomasz M Beer; George Wilding; Alison Martin; Maha Hussain
Journal:  J Clin Oncol       Date:  2008-03-01       Impact factor: 44.544

5.  Metastatic castrate-resistant prostate cancer with a late, complete and durable response to docetaxel chemotherapy: a case report.

Authors:  Luis Daverede; Christy Ralph; Satinder P Jagdev; Ioannis Trigonis; Sebastian Trainor; Patricia Harnden; Michael Weston; Alan Paul; Naveen S Vasudev
Journal:  J Med Case Rep       Date:  2014-04-09
  5 in total
  1 in total

1.  Bone density and pain response following intensity-modulated radiotherapy versus three-dimensional conformal radiotherapy for vertebral metastases - secondary results of a randomized trial.

Authors:  Tanja Sprave; Vivek Verma; Robert Förster; Ingmar Schlampp; Katharina Hees; Thomas Bruckner; Tilman Bostel; Rami Ateyah El Shafie; Thomas Welzel; Nils Henrik Nicolay; Jürgen Debus; Harald Rief
Journal:  Radiat Oncol       Date:  2018-10-30       Impact factor: 3.481

  1 in total

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