Literature DB >> 2776540

[Experimental study of antigastroesophageal reflux by preservation of the lower esophageal sphincter].

Y Yan.   

Abstract

Gastroesophageal reflux and its resultant esophagitis are common complications following removal of the middle and lower part of the esophagus as well as the gastric cardia with reconstruction by simple esophagogastrostomy. Twenty-one dogs were randomly divided into 3 groups: (1) LES preserving group; (2) Nissen's fundoplication group; (3) Sweet's esophagogastrostomy group. Results by esophageal manometry, X-ray video tape recorder, and pathological examination respectively, 3 months postoperatively were compared. Esophageal manometry showed that the pressure of the preserved LES was still present. X-ray video tape recorder revealed that antireflex function was present in the preserved LES. Pathological examination confirmed no signs of reflux esophagitis in the mucosal specimen of the preserved LES group. We concluded that LES is the main barrier of gastroesophageal reflux. The intrathoracic LES could still have the function of anti-reflux.

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Year:  1989        PMID: 2776540

Source DB:  PubMed          Journal:  Zhonghua Wai Ke Za Zhi        ISSN: 0529-5815


  1 in total

1.  Clinical outcome of lower esophageal sphincter- and vagus-nerve-preserving partial cardiectomy for early gastric cancer of the subcardia.

Authors:  Hideo Matsumoto; Haruaki Murakami; Hisako Kubota; Masaharu Higashida; Masafumi Nakamura; Toshihiro Hirai
Journal:  Gastric Cancer       Date:  2014-06-07       Impact factor: 7.370

  1 in total

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