BACKGROUND: It is not well understood whether age impacts transcranial Doppler (TCD) mean flow velocities (MFVs) in patients with aneurysmal subarachnoid hemorrhage (SAH) with or without delayed cerebral ischemia (DCI). The aim of our study was to analyze the behavior of TCD MFV during the first 7 days after SAH in patients of different ages and correlate them with the occurrence of DCI. METHODS: This study is a databank analysis of patients with SAH admitted between 2010 and 2012 in a single center. We analyzed mean MFV of bilateral middle cerebral arteries (MCAs) in all patients enrolled in the study on days 1, 3 and 7. The correlation between age and TCD MFV was analyzed using a univariate linear regression model. RESULTS: Fifty-five patients were studied. Starting on the third day after the bleeding, increasing age was associated with slower MFVs. This trend was not affected by the interrogation of the right or left MCA. After correction to include only patients who developed DCI, the same findings persisted on days 3 and 7. CONCLUSION: Older age was correlated with a significant decrease on TCD velocities in patients with SAH, even after correction for patients who developed DCI.
BACKGROUND: It is not well understood whether age impacts transcranial Doppler (TCD) mean flow velocities (MFVs) in patients with aneurysmal subarachnoid hemorrhage (SAH) with or without delayed cerebral ischemia (DCI). The aim of our study was to analyze the behavior of TCD MFV during the first 7 days after SAH in patients of different ages and correlate them with the occurrence of DCI. METHODS: This study is a databank analysis of patients with SAH admitted between 2010 and 2012 in a single center. We analyzed mean MFV of bilateral middle cerebral arteries (MCAs) in all patients enrolled in the study on days 1, 3 and 7. The correlation between age and TCD MFV was analyzed using a univariate linear regression model. RESULTS: Fifty-five patients were studied. Starting on the third day after the bleeding, increasing age was associated with slower MFVs. This trend was not affected by the interrogation of the right or left MCA. After correction to include only patients who developed DCI, the same findings persisted on days 3 and 7. CONCLUSION: Older age was correlated with a significant decrease on TCD velocities in patients with SAH, even after correction for patients who developed DCI.
Authors: Monica Fabiani; Kathy A Low; Chin-Hong Tan; Benjamin Zimmerman; Mark A Fletcher; Nils Schneider-Garces; Edward L Maclin; Antonio M Chiarelli; Bradley P Sutton; Gabriele Gratton Journal: Psychophysiology Date: 2014-08-06 Impact factor: 4.016
Authors: Mats Ryttlefors; Per Enblad; Elisabeth Ronne-Engström; Lennart Persson; Don Ilodigwe; R Loch Macdonald Journal: Neurosurgery Date: 2010-10 Impact factor: 4.654
Authors: Edouard Fonck; Georg G Feigl; Jean Fasel; Daniel Sage; Michael Unser; Daniel A Rüfenacht; Nikolaos Stergiopulos Journal: Stroke Date: 2009-05-28 Impact factor: 7.914
Authors: Alejandro A Rabinstein; Jonathan A Friedman; Stephen D Weigand; Robyn L McClelland; Jimmy R Fulgham; Edward M Manno; John L D Atkinson; Eelco F M Wijdicks Journal: Stroke Date: 2004-06-24 Impact factor: 7.914
Authors: Elke Kooijman; Cora H Nijboer; Cindy T J van Velthoven; Wouter Mol; Rick M Dijkhuizen; Jozef Kesecioglu; Cobi J Heijnen Journal: PLoS One Date: 2014-03-06 Impact factor: 3.240
Authors: Jan W Dankbaar; Mienke Rijsdijk; Irene C van der Schaaf; Birgitta K Velthuis; Marieke J H Wermer; Gabriel J E Rinkel Journal: Neuroradiology Date: 2009-07-22 Impact factor: 2.804