Literature DB >> 27763795

Zika Virus: The Agent and Its Biology, With Relevance to Pathology.

Carey L Medin, Alan L Rothman1.   

Abstract

Once obscure, Zika virus (ZIKV) has attracted significant medical and scientific attention in the past year because of large outbreaks associated with the recent introduction of this virus into the Western hemisphere. In particular, the occurrence of severe congenital infections and cases of Guillain-Barré syndrome has placed this virus squarely in the eyes of clinical and anatomic pathologists. This review article provides a basic introduction to ZIKV, its genetics, its structural characteristics, and its biology. A multidisciplinary effort will be essential to establish clinicopathologic correlations of the basic virology of ZIKV in order to advance development of diagnostics, therapeutics, and vaccines.

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Year:  2016        PMID： 27763795     DOI： 10.5858/arpa.2016-0409-RA

Source DB:  PubMed          Journal:  Arch Pathol Lab Med        ISSN： 0003-9985            Impact factor:   5.534


  9 in total

1.  Characterization of two engineered dimeric Zika virus envelope proteins as immunogens for neutralizing antibody selection and vaccine design.

Authors:  Chunpeng Yang; Fang Zeng; Xinyu Gao; Shaojuan Zhao; Xuan Li; Sheng Liu; Na Li; Chenglin Deng; Bo Zhang; Rui Gong
Journal:  J Biol Chem       Date:  2019-05-28       Impact factor: 5.157

2.  Synthesis, structure-activity relationship and antiviral activity of indole-containing inhibitors of Flavivirus NS2B-NS3 protease.

Authors:  Shenyou Nie; Jidong Zhao; Xiaowei Wu; Yuan Yao; Fangrui Wu; Yi-Lun Lin; Xin Li; Alexander R Kneubehl; Megan B Vogt; Rebecca Rico-Hesse; Yongcheng Song
Journal:  Eur J Med Chem       Date:  2021-08-14       Impact factor: 6.514

Review 3.  Mucosal Vaccination: A Promising Alternative Against Flaviviruses.

Authors:  Rosendo Luria-Pérez; Luis A Sánchez-Vargas; Paola Muñoz-López; Gabriela Mellado-Sánchez
Journal:  Front Cell Infect Microbiol       Date:  2022-06-15       Impact factor: 6.073

Review 4.  T lymphocyte responses to flaviviruses - diverse cell populations affect tendency toward protection and disease.

Authors:  Luis Alberto Sanchez Vargas; Anuja Mathew; Alan L Rothman
Journal:  Curr Opin Virol       Date:  2020-08-15       Impact factor: 7.090

5.  Synthesis, Structure-Activity Relationships, and Antiviral Activity of Allosteric Inhibitors of Flavivirus NS2B-NS3 Protease.

Authors:  Shenyou Nie; Yuan Yao; Fangrui Wu; Xiaowei Wu; Jidong Zhao; Yuanda Hua; Jingyu Wu; Tong Huo; Yi-Lun Lin; Alexander R Kneubehl; Megan B Vogt; Josephine Ferreon; Rebecca Rico-Hesse; Yongcheng Song
Journal:  J Med Chem       Date:  2021-02-17       Impact factor: 7.446

6.  Critical neutralizing fragment of Zika virus EDIII elicits cross-neutralization and protection against divergent Zika viruses.

Authors:  Wanbo Tai; Lei He; Yufei Wang; Shihun Sun; Guangyu Zhao; Chuming Luo; Pei Li; Haiyan Zhao; Daved H Fremont; Fang Li; Shibo Jiang; Yusen Zhou; Lanying Du
Journal:  Emerg Microbes Infect       Date:  2018-01-24       Impact factor: 7.163

Review 7.  Targeting the RdRp of Emerging RNA Viruses: The Structure-Based Drug Design Challenge.

Authors:  Francesca Picarazzi; Ilaria Vicenti; Francesco Saladini; Maurizio Zazzi; Mattia Mori
Journal:  Molecules       Date:  2020-12-03       Impact factor: 4.411

8.  The Antiviral Drug Arbidol Inhibits Zika Virus.

Authors:  Susan L Fink; Lucia Vojtech; Jessica Wagoner; Natalie S J Slivinski; Konner J Jackson; Ruofan Wang; Sudip Khadka; Priya Luthra; Christopher F Basler; Stephen J Polyak
Journal:  Sci Rep       Date:  2018-06-12       Impact factor: 4.379

Review 9.  Maternal-Fetal Interplay in Zika Virus Infection and Adverse Perinatal Outcomes.

Authors:  Franciane Mouradian Emidio Teixeira; Anna Julia Pietrobon; Luana de Mendonça Oliveira; Luanda Mara da Silva Oliveira; Maria Notomi Sato
Journal:  Front Immunol       Date:  2020-02-14       Impact factor: 7.561
  9 in total

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