Literature DB >> 2776366

Demonstration of the organ preference of liver selected 'high metastatic' Lewis lung tumor cell line.

S Paku1, A Rot, A Ladányi, K Lapis.   

Abstract

The experimental metastasis patterns of 'low metastatic' Lewis lung tumor (LLT) and liver selected 'high metastatic' LLT-HH were studied following their arterial dissemination. In previous reports it was shown that both tumor lines develop metastases only in the first encountered organ. Here the liver preference of the liver selected cell line is demonstrated. The model of two LLT cell lines can provide experimental evidence for both the 'mechanical' and 'seed and soil' theories of metastasis formation, depending on the site of tumor cell injection.

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Year:  1989        PMID: 2776366     DOI: 10.1007/BF01753671

Source DB:  PubMed          Journal:  Clin Exp Metastasis        ISSN: 0262-0898            Impact factor:   5.150


  25 in total

1.  Organ specificity of blood-borne tumour metastasis determined by cell adhesion?

Authors:  G L Nicolson; J L Winkelhake
Journal:  Nature       Date:  1975-05-15       Impact factor: 49.962

2.  Organ-specific adhesion of metastatic tumor cells in vitro.

Authors:  P A Netland; B R Zetter
Journal:  Science       Date:  1984-06-08       Impact factor: 47.728

3.  Organ selectivity for implantation survival and growth of B16 melanoma variant tumor lines.

Authors:  I J Fidler; G L Nicolson
Journal:  J Natl Cancer Inst       Date:  1976-11       Impact factor: 13.506

4.  Comparative study on Lewis lung tumor lines with 'low' and 'high' metastatic capacity. II. Cytochemical and biochemical evidence for differences in glycosaminoglycans.

Authors:  J Timár; E Móczar; F Timár; K Pál; L Kopper; K Lapis; A Jeney
Journal:  Clin Exp Metastasis       Date:  1987 Jan-Mar       Impact factor: 5.150

5.  Organ preferences in metastatic colony formation by spontaneous mammary carcinomas after intra-arterial inoculation.

Authors:  S F Juacaba; L D Jones; D Tarin
Journal:  Invasion Metastasis       Date:  1983

6.  The stability of kidney-induced selection of Lewis lung tumor cell populations, and their metastasis-related behavior.

Authors:  L Weiss; P M Ward; J P Harlos
Journal:  Int J Cancer       Date:  1986-08-15       Impact factor: 7.396

Review 7.  Cell surface molecules and tumor metastasis. Regulation of metastatic phenotypic diversity.

Authors:  G L Nicolson
Journal:  Exp Cell Res       Date:  1984-01       Impact factor: 3.905

Review 8.  'Seed and soil' revisited: mechanisms of site-specific metastasis.

Authors:  I R Hart
Journal:  Cancer Metastasis Rev       Date:  1982       Impact factor: 9.264

9.  Metastatic behavior of a murine reticulum cell sarcoma exhibiting organ-specific growth.

Authors:  I R Hart; J E Talmadge; I J Fidler
Journal:  Cancer Res       Date:  1981-04       Impact factor: 12.701

10.  Characterization of two highly metastatic variants of Lewis lung carcinoma with different organ specificities.

Authors:  P Brodt
Journal:  Cancer Res       Date:  1986-05       Impact factor: 12.701

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  4 in total

1.  Organ-specificity of the extravasation process: an ultrastructural study.

Authors:  S Paku; B Döme; R Tóth; J Timár
Journal:  Clin Exp Metastasis       Date:  2000       Impact factor: 5.150

2.  Experimental and clinicopathologic studies on the function of the HGF receptor in human colon cancer metastasis.

Authors:  K Fazekas; O Csuka; I Köves; E Rásó; J Tímár
Journal:  Clin Exp Metastasis       Date:  2000       Impact factor: 5.150

3.  Morphological aspects of angiogenesis in experimental liver metastases.

Authors:  S Paku; K Lapis
Journal:  Am J Pathol       Date:  1993-09       Impact factor: 4.307

4.  Sex-dependent liver colonization of human melanoma in SCID mice--role of host defense mechanisms.

Authors:  Judit Dobos; Anita Mohos; József Tóvári; Erzsébet Rásó; Tamás Lőrincz; Gergely Zádori; József Tímár; Andrea Ladányi
Journal:  Clin Exp Metastasis       Date:  2012-12-01       Impact factor: 5.150

  4 in total

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