Literature DB >> 2776351

Human serum immuno-reactive copper, zinc-superoxide dismutase assayed with an enzyme monoclonal immunosorbent in patients with digestive cancer.

S Oka1, K Ogino, S Matsuura, S Yoshimura, K Yamamoto, Y Okazaki, T Takemoto, N Kato, T Uda.   

Abstract

Two types of monoclonal antibodies, N4 and N6, were raised against human copper, zinc-superoxide dismutase (Cu,Zn-SOD). An enzyme-linked immunosorbent assay for Cu,Zn-SOD was developed in sandwich method using these monoclonal antibodies. The measurable assay range was 1.0-100 micrograms/l and the coefficient of variation within and between series were 7.5% and 8.1%. Sera of 154 healthy control subjects displayed a low level (14 micrograms/l) of immunoreactive Cu,Zn-SOD with a logarithmic normal distribution. On the other hand, serum Cu,Zn-SOD levels were significantly elevated in patients with various digestive cancers.

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Year:  1989        PMID： 2776351     DOI： 10.1016/0009-8981(89)90079-x

Source DB:  PubMed          Journal:  Clin Chim Acta        ISSN： 0009-8981            Impact factor:   3.786


  6 in total

1.  Clinical significance of evaluation of serum zinc concentrations in C-viral chronic liver disease.

Authors:  Mitsuhiko Moriyama; Hiroshi Matsumura; Akiko Fukushima; Kenji Ohkido; Yasuo Arakawa; Kazushige Nirei; Hiroaki Yamagami; Miki Kaneko; Naohide Tanaka; Yasuyuki Arakawa
Journal:  Dig Dis Sci       Date:  2006-10-18       Impact factor: 3.199

2.  Zinc supplementation improves the outcome of chronic hepatitis C and liver cirrhosis.

Authors:  Shunichi Matsuoka; Hiroshi Matsumura; Hitomi Nakamura; Shu Oshiro; Yasuo Arakawa; Junpei Hayashi; Naoki Sekine; Kazushige Nirei; Hiroaki Yamagami; Masahiro Ogawa; Noriko Nakajima; Shuichi Amaki; Naohide Tanaka; Mitsuhiko Moriyama
Journal:  J Clin Biochem Nutr       Date:  2009-10-28       Impact factor: 3.114

3.  Superoxide Dismutase in Human Adrenal and its Disorders: A Correlation with Development and Neoplastic Changes.

Authors:  Hironobu Sasano; Aki Mizorogi; Michiko Sato; Hisayoshi Nakazumi; Takashi Suzuki
Journal:  Endocr Pathol       Date:  1999       Impact factor: 3.943

4.  Leucocytosis as a marker of organ damage induced by chronic strenuous physical exercise.

Authors:  S Kayashima; H Ohno; T Fujioka; N Taniguchi; N Nagata
Journal:  Eur J Appl Physiol Occup Physiol       Date:  1995

5.  Serum copper/zinc superoxide dismutase (Cu/Zn SOD) and gastric cancer risk: a case-control study.

Authors:  Yingsong Lin; Shogo Kikuchi; Yuki Obata; Kiyoko Yagyu
Journal:  Jpn J Cancer Res       Date:  2002-10

6.  Evaluation of Systemic Oxidative Stress in Patients with Premature Canities and Correlation of Severity of Hair Graying with the Degree of Redox Imbalance.

Authors:  Snigdha Saxena; Ram Krishan Gautam; Aastha Gupta; Anubhuti Chitkara
Journal:  Int J Trichology       Date:  2020-04-09
  6 in total

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