Literature DB >> 2775909

An analysis of the clinical relevance of type 1 and type 2 alcoholics.

M A Schuckit, M Irwin.   

Abstract

Predictions inherent in the proposed Type 1/Type 2 continuum of alcoholic subtypes were indirectly explored in 31 sons of primary alcoholic fathers. The fathers' alcoholism was rated on a 0-5 scale utilizing characteristics typical of the Type 2 extreme of the continuum. If a predisposition to Type 2 alcoholism is genetically transmitted, then we would have predicted that the sons of Type 2 alcoholics would be more likely than the sons of Type 1 men to show an earlier onset of drinking, as well as more alcohol and substance intake and associated problems. The results did not support any consistent trend in the correlation between the FHP fathers' alcoholic characteristics and the sons' problem picture. Potential explanations for this finding are discussed including the possibility that the Type 2 extreme might represent a separate diagnostic entity, the antisocial personality disorder, and not alcoholism itself.

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Year:  1989        PMID: 2775909     DOI: 10.1111/j.1360-0443.1989.tb00759.x

Source DB:  PubMed          Journal:  Br J Addict        ISSN: 0952-0481


  4 in total

Review 1.  Gene-environment interplay in alcoholism and other substance abuse disorders: expressions of heritability and factors influencing vulnerability.

Authors:  Tomas Palomo; R M Kostrzewa; R J Beninger; T Archer
Journal:  Neurotox Res       Date:  2004       Impact factor: 3.911

2.  The familial transmission of alcoholism.

Authors:  E J Marshall; R M Murray
Journal:  BMJ       Date:  1991-07-13

3.  A new definition of early age at onset in alcohol dependence.

Authors:  Yann Le Strat; Bridget F Grant; Nicolas Ramoz; Philip Gorwood
Journal:  Drug Alcohol Depend       Date:  2009-12-16       Impact factor: 4.492

4.  Age at onset typology in opioid dependent men: an exploratory study.

Authors:  Biswajit De; Surendra K Mattoo; Debasish Basu
Journal:  Indian J Psychiatry       Date:  2002-04       Impact factor: 1.759

  4 in total

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