Literature DB >> 27757815

NUT Midline Carcinoma of the Nasal Cavity.

Mia Edgar1, Andria M Caruso2, Esther Kim2, Robert D Foss3.   

Abstract

Nuclear protein in testis (NUT) midline carcinoma (NMC) is a rare, aggressive, poorly differentiated form of squamous cell carcinoma caused by a chromosomal rearrangement of the NUT gene on chromosome 15. These tumors have a predilection for midline and paramidline structures of the upper aerodigestive tract and mediastinum and can affect patients across a broad age range, including children. In the current example, a 53 year old male presented with a mass originating in the left nasal cavity. The clinical, radiographic, and morphologic features of NMC are discussed.

Entities:  

Keywords:  NUT midline carcinoma; Nasal; Nasal cavity; Nuclear protein of testis; Radiology; Sinonasal; Undifferentiated carcinoma

Mesh：

Substances：

Year:  2016        PMID： 27757815      PMCID： PMC5550387          DOI： 10.1007/s12105-016-0763-0

Source DB:  PubMed          Journal:  Head Neck Pathol        ISSN： 1936-055X


  8 in total

1.  Clinicopathological significance of NUT rearrangements in poorly differentiated malignant tumors of the upper respiratory tract.

Authors:  Wei Fang; Christopher A French; Michael J Cameron; Yiding Han; Honggang Liu
Journal:  Int J Surg Pathol       Date:  2012-07-09       Impact factor: 1.271

Review 2.  A review of NUT midline carcinoma.

Authors:  Edward B Stelow
Journal:  Head Neck Pathol       Date:  2011-01-08

3.  Clinicopathologic features and long-term outcomes of NUT midline carcinoma.

Authors:  Daniel E Bauer; Chelsey M Mitchell; Kelly M Strait; Christopher S Lathan; Edward B Stelow; Sonja C Lüer; Somala Muhammed; Andrew G Evans; Lynette M Sholl; Juan Rosai; Eugenia Giraldi; Richard P Oakley; Carlos Rodriguez-Galindo; Wendy B London; Stephen E Sallan; James E Bradner; Christopher A French
Journal:  Clin Cancer Res       Date:  2012-08-15       Impact factor: 12.531

Review 4.  Squamous cell carcinoma variants of the upper aerodigestive tract: a comprehensive review with a focus on genetic alterations.

Authors:  Akeesha A Shah; Susanne K Jeffus; Edward B Stelow
Journal:  Arch Pathol Lab Med       Date:  2014-06       Impact factor: 5.534

Review 5.  Demystifying NUT midline carcinoma: radiologic and pathologic correlations of an aggressive malignancy.

Authors:  Ryan J Bair; Jeffrey F Chick; Nikunj R Chauhan; Christopher French; Rachna Madan
Journal:  AJR Am J Roentgenol       Date:  2014-10       Impact factor: 3.959

Review 6.  The importance of diagnosing NUT midline carcinoma.

Authors:  Christopher A French
Journal:  Head Neck Pathol       Date:  2013-03-05

Review 7.  Demystified molecular pathology of NUT midline carcinomas.

Authors:  Christopher A French
Journal:  J Clin Pathol       Date:  2008-06-13       Impact factor: 3.411

Review 8.  Carcinomas of the upper aerodigestive tract with rearrangement of the nuclear protein of the testis (NUT) gene (NUT midline carcinomas).

Authors:  Edward B Stelow; Christopher A French
Journal:  Adv Anat Pathol       Date:  2009-03       Impact factor: 3.875
  8 in total
  4 in total

Review 1.  Imaging Review of New and Emerging Sinonasal Tumors and Tumor-Like Entities from the Fourth Edition of the World Health Organization Classification of Head and Neck Tumors.

Authors:  K E Dean; D Shatzkes; C D Phillips
Journal:  AJNR Am J Neuroradiol       Date:  2019-02-14       Impact factor: 3.825

Review 2.  High-Grade Sinonasal Carcinoma: Classification Through Molecular Profiling.

Authors:  Julie Guilmette; Peter M Sadow
Journal:  Arch Pathol Lab Med       Date:  2019-02-19       Impact factor: 5.534

3.  Case report: NUT carcinoma in an elderly woman with unique morphology and immunophenotype highlights a diagnostic pitfall.

Authors:  Xuejing Wei; Xiaojing Teng; Yanning Zhang; Ming Cheng; Guangyong Chen
Journal:  Transl Cancer Res       Date:  2022-06       Impact factor: 0.496

4.  HPV-Related Multiphenotypic Sinonasal Carcinoma: Four Cases that Expand the Morpho-Molecular Spectrum and Include Occupational Data.

Authors:  Niels J Rupp; Ulrike Camenisch; Kati Seidl; Elisabeth J Rushing; Nanina Anderegg; Martina A Broglie; David Holzmann; Grégoire B Morand
Journal:  Head Neck Pathol       Date:  2019-09-30
  4 in total

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