| Literature DB >> 27757493 |
Eva Lassemo1, Inger Sandanger2, Jan F Nygård3, Knut W Sørgaard2,4.
Abstract
PURPOSE: The prevalence of PTSD differs by gender. Pre-existing psychiatric disorders and different traumas experienced by men and women may explain this. The aims of this study were to assess (1) incidence and prevalence of exposure to traumatic events and PTSD, (2) the effect of pre-existing psychiatric disorders prior to trauma on the risk for PTSD, and (3) the effect the characteristics of trauma have on the risk for PTSD. All stratified by gender.Entities:
Keywords: Epidemiology; Gender differences; Post-traumatic stress disorder; Pre-existing psychiatric disorders; Trauma
Mesh:
Year: 2016 PMID: 27757493 PMCID: PMC5226978 DOI: 10.1007/s00127-016-1295-3
Source DB: PubMed Journal: Soc Psychiatry Psychiatr Epidemiol ISSN: 0933-7954 Impact factor: 4.328
Study population stratified on gender, trauma exposure, and pre-existing psychiatric diagnoses. Weighted by age and gender
| At risk for PTE ( | At risk for PTSD ( | |||
|---|---|---|---|---|
| Women ( | Men ( | Women ( | Men ( | |
| Proportion exposed to PTE/with PTSD (%) | 20.6 | 25.9* | 20.6* | 5.6 |
| Mean age at worst traumatic exposure (95 % CI) | 24.1 (21.9–26.3) | 23.0 (21.9–24.0) | 20.2 (15.5–24.8) | 19.3 (13.1–25.6) |
| Mean age at onset PTSD (95 % CI) | 24.8 (20.1–29.6) | 19.9 (13.3–26.5) | ||
| Mean years from worst traumatic exposure to PTSD (95 % CI) | – | – | 4.7 (1.2–8.1) | 0.5 (−0.3 to 1.3) |
| Mean years of duration of PTSD (95 % CI) | – | – | 9.1 (5.3–12.9) | 17.2 (6.9–27.6) |
| Psychiatric disorder pre-existing to trauma and PTSD | ||||
| None (%) | 61.1 | 84.4* | 36.4 | 92.9* |
| Depression | 11.3* | 4.2 | 19.7 | 0.0 |
| Anxiety | 16.9* | 7.4 | 43.9* | 7.1 |
| Somatoform disorder | 25.3* | 9.5 | 44.9* | 0.0 |
| Any pre-existing disorder | 38.9* | 15.2 | 63.6* | 7.1 |
Gender difference tested statistically
Results are weighted to the Norwegian population
* p < 0.05
Odds ratio (ORs) for post-traumatic stress disorder (PTSD) following exposure to traumatic event and pre-existing psychiatric disorders and by trauma type
| Subsequent PTSD | ||||
|---|---|---|---|---|
| Women | Men | |||
| OR | 95 % CI | OR | 95 % CI | |
| Pre-existing psychiatric disordera | ||||
| Depressive disorder | 2.5 | (1.6–3.8) | – | |
| Anxiety disorder | 7.0 | (4.9–10.1) | 0.9 | (0.5–1.6) |
| Somatoform disorder | 3.2 | (2.3–4.4) | – | |
| Any disorder | 3.6 | (2.6–5.0) | 0.3 | (0.2–0.6) |
| No disorder | 0.3 | (0.2–0.4) | 3.1 | (1.8–5.1) |
| Trauma type | ||||
| Accidental | 1 | (ref) | 1 | (ref) |
| Premediated | 57.0 | (7.3–447.9) | 5.6 | (1.3–24.8) |
| Both | 95.6 | (11.0–831.3) | 1.3 | (0.2–7.6) |
Weighted by age and gender
Results are weighted to the Norwegian population
aDisorder with an age at onset earlier than age at worst traumatic exposure
Fig. 1Kaplan–Meier survival curves depicting probability of experiencing potentially traumatic events (panel 1) and fulfilling PTSD diagnostic criteria (panel 2) if suffering from any pre-existing psychiatric disorder and not, for women and men. Time at risk from birth. Note: Results are weighted to the Norwegian population
Lifetime prevalence of exposure to potentially traumatic events (PTEs) and conditional post-traumatic stress disorder (PTSD) by gender
| Traumatic event | At risk for PTE ( | At risk for PTSD ( | Pa lifetime trauma exposure | P1 PTSD | ||
|---|---|---|---|---|---|---|
| Women ( | Men ( | Women ( | Men ( | |||
| Any traumatic event | 20.6 | 25.9 | 20.6 | 5.6 | 0.018*♂ | 0.001*♀ |
| 1. War event | 2.3 | 3.9 | 4.4 | 6.3 | 0.086 | 0.773 |
| 2. Physical threat (weapon) | 6.4 | 8.1 | 33.5 | 2.8 | 0.218 | <0.001*♀ |
| 3. Rape | 3.2 | 0.1 | 54.5 | 0 | <0.001*♀ | – |
| 4. Sexual abuse as a child | 3.2 | 1.2 | 53.6 | 36.6 | 0.011*♀ | 0.450 |
| 5. Natural catastrophe | 2.0 | 1.4 | 3.7 | 9.1 | 0.357 | 0.521 |
| 6. Serious accident | 4.4 | 9.8 | 10.9 | 4.4 | <0.001*♂ | 0.233 |
| 7. Imprisoned, taken hostage, kidnapped | 0.8 | 3.1 | 24.6 | 7.3 | 0.004*♂ | 0.360 |
| 8. Witness above events happen to others | 3.9 | 9.4 | 17.0 | 3.5 | <0.001*♂ | 0.014*♀ |
| 9. Other | 4.0 | 3.7 | 31.2 | 11.8 | 0.710 | 0.102 |
| Verbal threat/violence from close relation |
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| Verbal threat/violence from non-close relation |
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| Two or more events | 6.8 | 8.5 | 34.8 | 5.3 | 0.221 | <0.001*♀ |
| Accidental | 41.8 | 56.1 | 1.7 | 30.3 | 0.010*♂ | 0.001*♂ |
| Premediated | 43.4 | 20.3 | 68.3 | 54.1 | <0.001*♀ | 0.449 |
| Both | 13.8 | 22.3 | 30.0 | 15.7 | 0.043*♂ | 0.370 |
Trauma type given exposed to trauma and given PTSD caseness by gender. Weighted by age and gender
Results are weighted to the Norwegian population
aFisher’s exact test
* Significant on the 95 % level
♀ Significantly different in direction of women
♂ Significantly different in direction of men