Literature DB >> 27757310

Zfra induction of memory anticancer response via a novel immune cell.

Wan-Pei Su1, Wan-Jan Wang1, Chun-I Sze2, Nan-Shan Chang3.   

Abstract

When naive mice receive short Zfra peptides via tail vein injections, they develop lifetime resistance to growth of many cancer xenografts, due to activation of a novel spleen memory Hyal-2+ CD3- CD19- Z lymphocyte. In vitro education of spleen cells with Zfra activates Z cell for conferring memory anticancer response in vivo.

Entities:  

Keywords:  Zfra; Hyal-2+ CD3- CD19-; Hyaluronidase Hyal-2; Z lymphocyte; memory anticancer response

Year:  2016        PMID： 27757310      PMCID： PMC5048772          DOI： 10.1080/2162402X.2016.1213935

Source DB:  PubMed          Journal:  Oncoimmunology        ISSN： 2162-4011            Impact factor:   8.110


  8 in total

1.  Cloning and characterization of a small-size peptide Zfra that regulates the cytotoxic function of tumor necrosis factor by interacting with JNK1.

Authors:  Li-Jin Hsu; Lori Schultz; Jeffrey Mattison; Yee-Shin Lin; Nan-Shan Chang
Journal:  Biochem Biophys Res Commun       Date:  2005-02-11       Impact factor: 3.575

Review 2.  Signaling from membrane receptors to tumor suppressor WW domain-containing oxidoreductase.

Authors:  Jean-Yun Chang; Ruei-Yu He; Hsin-Ping Lin; Li-Jin Hsu; Feng-Jie Lai; Qunying Hong; Shean-Jen Chen; Nan-Shan Chang
Journal:  Exp Biol Med (Maywood)       Date:  2010-06-11

3.  Hyaluronidase induction of a WW domain-containing oxidoreductase that enhances tumor necrosis factor cytotoxicity.

Authors:  N S Chang; N Pratt; J Heath; L Schultz; D Sleve; G B Carey; N Zevotek
Journal:  J Biol Chem       Date:  2000-10-31       Impact factor: 5.157

4.  Zfra is an inhibitor of Bcl-2 expression and cytochrome c release from the mitochondria.

Authors:  Li-Jin Hsu; Qunying Hong; Lori Schultz; Emory Kuo; Sing-Ru Lin; Ming-Hui Lee; Yee-Shin Lin; Nan-Shan Chang
Journal:  Cell Signal       Date:  2008-03-04       Impact factor: 4.315

5.  Transforming growth factor beta1 signaling via interaction with cell surface Hyal-2 and recruitment of WWOX/WOX1.

Authors:  Li-Jin Hsu; Lori Schultz; Qunying Hong; Kris Van Moer; John Heath; Meng-Yen Li; Feng-Jie Lai; Sing-Ru Lin; Ming-Hui Lee; Cheng-Peng Lo; Yee-Shin Lin; Shur-Tzu Chen; Nan-Shan Chang
Journal:  J Biol Chem       Date:  2009-04-14       Impact factor: 5.157

6.  Zfra is a small wizard in the mitochondrial apoptosis.

Authors:  Subhan Dudekula; Ming-Hui Lee; Li-Jin Hsu; Shean-Jen Chen; Nan-Shan Chang
Journal:  Aging (Albany NY)       Date:  2010-12       Impact factor: 5.682

7.  Zfra affects TNF-mediated cell death by interacting with death domain protein TRADD and negatively regulates the activation of NF-kappaB, JNK1, p53 and WOX1 during stress response.

Authors:  Qunying Hong; Li-Jin Hsu; Lori Schultz; Nicole Pratt; Jeffrey Mattison; Nan-Shan Chang
Journal:  BMC Mol Biol       Date:  2007-06-13       Impact factor: 2.946

8.  Zfra activates memory Hyal-2+ CD3- CD19- spleen cells to block cancer growth, stemness, and metastasis in vivo.

Authors:  Ming-Hui Lee; Wan-Pei Su; Wan-Jen Wang; Sing-Ru Lin; Chen-Yu Lu; Yu-An Chen; Jean-Yun Chang; Shenq-Shyang Huang; Pei-Yi Chou; Siou-Ru Ye; Szu-Jung Chen; Huan He; Ting-Hsiu Liu; Ying-Tsen Chou; Li-Jin Hsu; Feng-Jie Lai; Shean-Jen Chen; Hoong-Chien Lee; David Kakhniashvili; Steven R Goodman; Nan-Shan Chang
Journal:  Oncotarget       Date:  2015-02-28
  8 in total
  4 in total

1.  Zfra restores memory deficits in Alzheimer's disease triple-transgenic mice by blocking aggregation of TRAPPC6AΔ, SH3GLB2, tau, and amyloid β, and inflammatory NF-κB activation.

Authors:  Ming-Hui Lee; Yao-Hsiang Shih; Sing-Ru Lin; Jean-Yun Chang; Yu-Hao Lin; Chun-I Sze; Yu-Min Kuo; Nan-Shan Chang
Journal:  Alzheimers Dement (N Y)       Date:  2017-03-06

Review 2.  A Trickster in Disguise: Hyaluronan's Ambivalent Roles in the Matrix.

Authors:  Lena Bohaumilitzky; Ann-Kathrin Huber; Eva Maria Stork; Simon Wengert; Franziska Woelfl; Heike Boehm
Journal:  Front Oncol       Date:  2017-10-09       Impact factor: 6.244

Review 3.  WWOX Controls Cell Survival, Immune Response and Disease Progression by pY33 to pS14 Transition to Alternate Signaling Partners.

Authors:  Tsung-Yun Liu; Ganesan Nagarajan; Ming-Fu Chiang; Shenq-Shyang Huang; Tzu-Chia Lin; Yu-An Chen; Chun-I Sze; Nan-Shan Chang
Journal:  Cells       Date:  2022-07-07       Impact factor: 7.666

4.  WWOX Possesses N-Terminal Cell Surface-Exposed Epitopes WWOX7-21 and WWOX7-11 for Signaling Cancer Growth Suppression and Prevention In Vivo.

Authors:  Wan-Jen Wang; Pei-Chuan Ho; Ganesan Nagarajan; Yu-An Chen; Hsiang-Ling Kuo; Dudekula Subhan; Wan-Pei Su; Jean-Yun Chang; Chen-Yu Lu; Katarina T Chang; Sing-Ru Lin; Ming-Hui Lee; Nan-Shan Chang
Journal:  Cancers (Basel)       Date:  2019-11-19       Impact factor: 6.639
  4 in total

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