Literature DB >> 27757162

A case report of obstetrical management of a pregnancy with hypermobile Ehlers-Danlos syndrome and literature review.

H Khalil1, J Rafi1, T T Hla1.   

Abstract

We present a case report of a successful pregnancy outcome in a woman diagnosed with Ehlers-Danlos syndrome (EDS) hypermobility type or type III. EDS is a group of connective tissue disorders that has a common genotypic defect, but heterogeneous phenotypic presentations. The variation in EDS manifestations can result in moderate to severe effects on life-expectancy for some types. A number of studies and a review of the literature indicate that generally in pregnant women with EDS, maternal and neonatal outcomes are favourable. However, in EDS type IV, pregnancy can be associated with serious maternal complications. Therefore, obstetrical management should be individualized. This paper discusses the obstetric management of a patient with EDS hypermobility type and compares it to other studies in the literature.

Entities:  

Keywords:  Ehlers-Danlos syndrome

Year:  2013        PMID: 27757162      PMCID: PMC5052764          DOI: 10.1177/1753495X13482894

Source DB:  PubMed          Journal:  Obstet Med        ISSN: 1753-495X


  11 in total

Review 1.  Ehlers-Danlos syndrome type III and pregnancy. A case report.

Authors:  E P Sakala; M D Harding
Journal:  J Reprod Med       Date:  1991-08       Impact factor: 0.142

Review 2.  Ehlers-Danlos syndrome: insights on obstetric aspects.

Authors:  Natalie Volkov; Victoria Nisenblat; Gonen Ohel; Ron Gonen
Journal:  Obstet Gynecol Surv       Date:  2007-01       Impact factor: 2.347

3.  Ehlers-Danlos syndromes: revised nosology, Villefranche, 1997. Ehlers-Danlos National Foundation (USA) and Ehlers-Danlos Support Group (UK).

Authors:  P Beighton; A De Paepe; B Steinmann; P Tsipouras; R J Wenstrup
Journal:  Am J Med Genet       Date:  1998-04-28

4.  Ehlers-Danlos syndrome type III in pregnancy.

Authors:  A Atalla; I Page
Journal:  Obstet Gynecol       Date:  1988-03       Impact factor: 7.661

5.  Ehlers-Danlos syndrome and pregnancy: association of type IV disease with maternal death.

Authors:  A M Peaceman; D P Cruikshank
Journal:  Obstet Gynecol       Date:  1987-03       Impact factor: 7.661

6.  Obstetrical problems in patients with Ehlers-Danlos syndrome type IV; a case report.

Authors:  A De Paepe; B Thaler; M Van Gijsegem; D Van Hoecke; M Matton
Journal:  Eur J Obstet Gynecol Reprod Biol       Date:  1989-11       Impact factor: 2.435

7.  Pregnancy and the Ehlers-Danlos syndrome: a retrospective study in a Dutch population.

Authors:  Jan Lind; Henk C S Wallenburg
Journal:  Acta Obstet Gynecol Scand       Date:  2002-04       Impact factor: 3.636

8.  Echocardiographic findings in classical and hypermobile Ehlers-Danlos syndromes.

Authors:  Nazli B McDonnell; Beverly L Gorman; Katherine W Mandel; Shepherd H Schurman; Alison Assanah-Carroll; Susan A Mayer; Samer S Najjar; Clair A Francomano
Journal:  Am J Med Genet A       Date:  2006-01-15       Impact factor: 2.802

9.  Obstetric and gynecologic dysfunction in the Ehlers-Danlos syndrome.

Authors:  Y Sorokin; M P Johnson; N Rogowski; D A Richardson; M I Evans
Journal:  J Reprod Med       Date:  1994-04       Impact factor: 0.142

10.  Complications of the Ehlers-Danlos syndrome in pregnancy. A case report.

Authors:  M E Rivera-Alsina; P Kwan; F G Zavisca; S Hopkins; E Abouleish
Journal:  J Reprod Med       Date:  1984-10       Impact factor: 0.142

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  2 in total

1.  Ehlers-Danlos syndrome and other heritable connective tissue disorders that impact pregnancies can be detected using next-generation DNA sequencing.

Authors:  Krystal VanderJagt; Merlin G Butler
Journal:  Arch Gynecol Obstet       Date:  2019-06-27       Impact factor: 2.344

Review 2.  Hypermobile Ehlers-Danlos syndromes: Complex phenotypes, challenging diagnoses, and poorly understood causes.

Authors:  Cortney Gensemer; Randall Burks; Steven Kautz; Daniel P Judge; Mark Lavallee; Russell A Norris
Journal:  Dev Dyn       Date:  2020-08-17       Impact factor: 3.780

  2 in total

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