Literature DB >> 27754781

Quantification of leakage of sub-micron aerosols through surgical masks and facemasks for pediatric use.

Suvajyoti Guha1, Brady McCaffrey2, Prasanna Hariharan1, Matthew R Myers1.   

Abstract

Surgical respirators, surgical masks (SMs), and facemasks for pediatric use (FPUs) are routinely used in the U.S. healthcare industry as personal protective equipment (PPE) against infectious diseases. While N95s including surgical respirators have been routinely studied, SMs and FPUs have not received as much attention, particularly in the context of aerosolized threats. This is because SMs and PFUs are not designed to protect against sub-micron aerosols. However, with the possibility of new or re-emerging airborne diseases or bio-aerosol weapons lingering, combined with the limited availability of respirators and logistical issues associated with fit-testing millions, the general adult and pediatric populations may elect to wear SMs and FPUs, respectively, in the case of a pandemic or a bio-terrorist attack. When a person dons a PPE, gaps are created between the wearer's face and the PPE, and aerosols leaking through these gaps can be an important contributor to the risk of infection compared to filtered aerosols. To understand and quantify the contribution of leakage of aerosols through gaps, with particular emphasis on SMs and FPUs, this study investigated leakage of charge-neutralized, polydispersed, dried sodium-chloride aerosols across different brands of PPE. Different breathing rates, aerosol particle sizes, and gap sizes were considered. A few major findings of this study were: (a) leakage, is not a strong function of sub-micron aerosol size; (b) for the same gap size, leakage of aerosols through surgical respirators can often be higher than in SMs and FPUs; and (c) as the gap size increases, the increase in leakage through surgical respirators is higher compared for SMs and FPUs, implying that some SMs and FPUs that possess electret layers may be preferable to N95s that have not been fit-tested. The results obtained can also be used to explain conflicting findings from clinical studies on the effectiveness of SMs when compared to N95s and can be input into risk-assessment models to determine the increase in infection rate resulting from deployment of PPE under less-than-ideal conditions.

Entities:  

Keywords:  Filter; N95; leakage; pediatric facemasks; surgical facemasks

Mesh:

Substances:

Year:  2017        PMID: 27754781     DOI: 10.1080/15459624.2016.1237029

Source DB:  PubMed          Journal:  J Occup Environ Hyg        ISSN: 1545-9624            Impact factor:   2.155


  10 in total

1.  A computational model for predicting changes in infection dynamics due to leakage through N95 respirators.

Authors:  Prasanna Hariharan; Neha Sharma; Suvajyoti Guha; Rupak K Banerjee; Gavin D'Souza; Matthew R Myers
Journal:  Sci Rep       Date:  2021-05-21       Impact factor: 4.996

2.  Side-leakage of face mask.

Authors:  B N J Persson
Journal:  Eur Phys J E Soft Matter       Date:  2021-06-05       Impact factor: 1.890

3.  Estimation of effects of contact tracing and mask adoption on COVID-19 transmission in San Francisco: a modeling study.

Authors:  Lee Worden; Rae Wannier; Seth Blumberg; Alex Y Ge; George W Rutherford; Travis C Porco
Journal:  medRxiv       Date:  2020-06-11

4.  Comparison of bacterial filtration efficiency vs. particle filtration efficiency to assess the performance of non-medical face masks.

Authors:  Henrietta Essie Whyte; Yoann Montigaud; Estelle Audoux; Paul Verhoeven; Amélie Prier; Lara Leclerc; Gwendoline Sarry; Coralie Laurent; Laurence Le Coq; Aurélie Joubert; Jérémie Pourchez
Journal:  Sci Rep       Date:  2022-01-24       Impact factor: 4.379

Review 5.  What We Are Learning from COVID-19 for Respiratory Protection: Contemporary and Emerging Issues.

Authors:  Rui Li; Mengying Zhang; Yulin Wu; Peixin Tang; Gang Sun; Liwen Wang; Sumit Mandal; Lizhi Wang; James Lang; Alberto Passalacqua; Shankar Subramaniam; Guowen Song
Journal:  Polymers (Basel)       Date:  2021-11-28       Impact factor: 4.329

6.  Advancing Regulatory Science With Computational Modeling for Medical Devices at the FDA's Office of Science and Engineering Laboratories.

Authors:  Tina M Morrison; Pras Pathmanathan; Mariam Adwan; Edward Margerrison
Journal:  Front Med (Lausanne)       Date:  2018-09-25

Review 7.  An overview of filtration efficiency through the masks: Mechanisms of the aerosols penetration.

Authors:  A Tcharkhtchi; N Abbasnezhad; M Zarbini Seydani; N Zirak; S Farzaneh; M Shirinbayan
Journal:  Bioact Mater       Date:  2020-08-11

8.  A randomised clinical trial to evaluate the safety, fit, comfort of a novel N95 mask in children.

Authors:  Daniel Yam Thiam Goh; Meng Wai Mun; Wei Liang Jerome Lee; Oon Hoe Teoh; Dimple D Rajgor
Journal:  Sci Rep       Date:  2019-12-12       Impact factor: 4.379

Review 9.  Health effects of wildfire smoke in children and public health tools: a narrative review.

Authors:  Stephanie M Holm; Mark D Miller; John R Balmes
Journal:  J Expo Sci Environ Epidemiol       Date:  2020-09-20       Impact factor: 5.563

Review 10.  Processing and Quality Control of Masks: A Review.

Authors:  Sedigheh Farzaneh; Mohammadali Shirinbayan
Journal:  Polymers (Basel)       Date:  2022-01-11       Impact factor: 4.329

  10 in total

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