| Literature DB >> 27753509 |
Abstract
In the spring of 2015, 11 years after a mentally ill young man named Dan Markingson stabbed himself to death in an industry-sponsored drug study, officials at the University of Minnesota suspended recruitment of subjects into drug trials in its Department of Psychiatry. University officials agreed to act only after a scathing investigation by Minnesota Office of the Legislative Auditor found damning evidence of coerced recruitment, inadequate clinical care, superficial research oversight, a web of serious, disturbing conflicts of interest, and a pattern of misleading public statements by university officials aimed at deflecting scrutiny. In this article, I examine the larger institutional factors leading up to Markingson's suicide and prevented corrective action for so long.Entities:
Keywords: Conflict of interest; human subjects ethics; human subjects regulation and oversight; informed consent; misconduct in research; organizational and institutional ethics; research ethics; research ethics in university contexts; research on the mentally ill; vulnerable populations
Mesh:
Substances:
Year: 2016 PMID: 27753509 DOI: 10.1080/08989621.2016.1246969
Source DB: PubMed Journal: Account Res ISSN: 0898-9621 Impact factor: 2.622