Literature DB >> 27752782

[Current diagnostics and therapy recommendations for ocular basal cell carcinoma].

V Kakkassery1, K U Loeffler2, M Sand3,4, K R Koch5, A M Lentzsch5, A C Nick6, I A Adamietz7, L M Heindl5.   

Abstract

The treatment options for basal cell carcinoma (BCC) have recently been augmented with the introduction of novel chemotherapeutic drugs. New S2 guidelines on the disease have also been published. The aim of this article is to present a comprehensive state of the art description of the features of ocular BCC and an overview of the various therapeutic options. Particular emphasis is placed on the clinical signs, the diagnostic tools to identify periocular BCC and interpretation of the different histopathological subtypes. Tumor staging, TNM classification, interdisciplinary tumor conference reviews as well as psycho-oncological services play an important role in patients with pronounced periocular BCC. Surgical removal with a histological R0 resection is an important component of therapy options in this disease and includes the microsurgical excision into healthy tissue and the subsequent covering of the defect. A special focus of this article is the treatment of locally extensive and metastasized BCC.

Entities:  

Keywords:  Chemotherapeutic drugs; Histology; Microsurgery; Pathology; Tumors

Mesh:

Year:  2017        PMID: 27752782     DOI: 10.1007/s00347-016-0370-1

Source DB:  PubMed          Journal:  Ophthalmologe        ISSN: 0941-293X            Impact factor:   1.059


  52 in total

1.  [Comparison of the aesthetic outcome and complication rate of reconstructive surgical procedures of the eyelid after basalioma excision].

Authors:  V Engelmann; S Pfrommer; M J Dridi; J Piening; C P Lohmann; R-L Merté
Journal:  Ophthalmologe       Date:  2011-01       Impact factor: 1.059

Review 2.  Basal-cell carcinoma.

Authors:  Adam I Rubin; Elbert H Chen; Désirée Ratner
Journal:  N Engl J Med       Date:  2005-11-24       Impact factor: 91.245

3.  Hedgehog Pathway Inhibition for Locally Advanced Periocular Basal Cell Carcinoma and Basal Cell Nevus Syndrome.

Authors:  Omar K Ozgur; Vivian Yin; Eva Chou; Sharon Ball; Merrill Kies; William N William; Michael Migden; Bradley A Thuro; Bita Esmaeli
Journal:  Am J Ophthalmol       Date:  2015-04-30       Impact factor: 5.258

4.  Role of PTCH and p53 genes in early-onset basal cell carcinoma.

Authors:  H Zhang; X L Ping; P K Lee; X L Wu; Y J Yao; M J Zhang; D N Silvers; D Ratner; R Malhotra; M Peacocke; H C Tsou
Journal:  Am J Pathol       Date:  2001-02       Impact factor: 4.307

Review 5.  Utility of radiotherapy for treatment of basal cell carcinoma: a review.

Authors:  M Cho; L Gordon; A Rembielak; T C S Woo
Journal:  Br J Dermatol       Date:  2014-10-26       Impact factor: 9.302

6.  Secondary Resistance to Vismodegib After Initial Successful Treatment of Extensive Recurrent Periocular Basal Cell Carcinoma with Orbital Invasion.

Authors:  Vasilios P Papastefanou; Cornelius René
Journal:  Ophthalmic Plast Reconstr Surg       Date:  2017 May/Jun       Impact factor: 1.746

7.  Phase I trial of hedgehog pathway inhibitor vismodegib (GDC-0449) in patients with refractory, locally advanced or metastatic solid tumors.

Authors:  Patricia M LoRusso; Charles M Rudin; Josina C Reddy; Raoul Tibes; Glen J Weiss; Mitesh J Borad; Christine L Hann; Julie R Brahmer; Ilsung Chang; Walter C Darbonne; Richard A Graham; Kenn L Zerivitz; Jennifer A Low; Daniel D Von Hoff
Journal:  Clin Cancer Res       Date:  2011-02-07       Impact factor: 12.531

8.  [Utilisation of Psycho-oncological Services in Hospitals and Outpatient Counselling Centres by Survivors of Breast, Colon and Prostate Cancer].

Authors:  Sylke Ruth Zeissig; Susanne Singer; Lena Koch; Maria Blettner; Volker Arndt
Journal:  Psychother Psychosom Med Psychol       Date:  2014-12-08

9.  Electron beam therapy is not inferior to superficial x-ray therapy in the treatment of skin carcinoma.

Authors:  C Griep; J Davelaar; A N Scholten; A Chin; J W Leer
Journal:  Int J Radiat Oncol Biol Phys       Date:  1995-07-30       Impact factor: 7.038

10.  Effect of a structured psycho-oncological screening and treatment model on mental health in cancer patients (STEPPED CARE): study protocol for a cluster randomized controlled trial.

Authors:  Susanne Singer; Helge Danker; Susanne Briest; Arne Dietrich; Andreas Dietz; Jens Einenkel; Kirsten Papsdorf; Florian Lordick; Jürgen Meixensberger; Joachim Mössner; Dietger Niederwieser; Torsten Prietzel; Franziska Schiefke; Jens-Uwe Stolzenburg; Hubert Wirtz; Anette Kersting
Journal:  Trials       Date:  2014-12-10       Impact factor: 2.279

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  9 in total

Review 1.  [Surgical treatment of eyelid tumors].

Authors:  M A Varde; B Wiechens
Journal:  HNO       Date:  2018-10       Impact factor: 1.284

Review 2.  [Surgical resection with ophthalmoplastic reconstruction : Gold standard in periocular basal cell carcinoma].

Authors:  A C Rokohl; A Kopecky; Y Guo; V Kakkassery; J M Mor; N Loreck; K R Koch; L M Heindl
Journal:  Ophthalmologe       Date:  2020-02       Impact factor: 1.059

3.  [Periocular basal cell carcinoma].

Authors:  Ludwig M Heindl
Journal:  Ophthalmologe       Date:  2020-02       Impact factor: 1.059

4.  [Young male patient with unusual space-occupying lesion of the lower eyelid].

Authors:  Alexander C Rokohl; Heike Löser; Joel M Mor; Niklas Loreck; Konrad R Koch; Ludwig M Heindl
Journal:  Ophthalmologe       Date:  2020-01       Impact factor: 1.059

Review 5.  [Alternative treatment options for periorbital basal cell carcinoma].

Authors:  Vinodh Kakkassery; Steffen Emmert; Irenäus A Adamietz; György Kovács; Anselm M Jünemann; Caroline Otte; Michael Zimbelmann; Anton Brosig; Salvatore Grisanti; Ludwig M Heindl
Journal:  Ophthalmologe       Date:  2020-02       Impact factor: 1.059

6.  [Advanced periocular basal cell carcinoma-a therapeutic challenge].

Authors:  B Lauterbach; V Kakkassery; D Debus; L M Heindl; E S Schultz
Journal:  Ophthalmologe       Date:  2019-03       Impact factor: 1.059

7.  [Occult basal cell carcinoma intermingling with seborrheic keratosis of the eyelid : A clinicopathological case report].

Authors:  Simone Nuessle; Stefan J Lang; Claudia Auw-Haedrich
Journal:  Ophthalmologie       Date:  2021-05-27

8.  Effective treatment of locally advanced periocular basal cell carcinoma with oral hedgehog pathway inhibitor?

Authors:  Xiaoyi Hou; Alexander C Rokohl; Monika Ortmann; Ludwig M Heindl
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2020-06-09       Impact factor: 3.117

9.  Effective systemic treatment of advanced periocular basal cell carcinoma with sonidegib.

Authors:  Alexander C Rokohl; Ludwig M Heindl
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2021-08-02       Impact factor: 3.117

  9 in total

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