Literature DB >> 2775276

The primary structure of a membrane-associated phospholipase A2 from human spleen.

A Kanda1, T Ono, N Yoshida, H Tojo, M Okamoto.   

Abstract

The complete primary structure of membrane-associated phospholipase A2 purified from a human splenic membrane fraction was determined by sequence analysis of the peptides generated by lysyl endopeptidase and Staphylococcus aureus V8 protease cleavage. The enzyme consists of 124 amino acid residues corresponding to a molecular weight of 13,904. The primary structure reveals the characteristics of Group II phospholipases A2 and a large ratio of basic amino acid residues to acidic ones, that ratio being 3.4 : 1.

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Year:  1989        PMID： 2775276     DOI： 10.1016/0006-291x(89)92096-2

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  12 in total

1.  Raised serum activity of phospholipase A2 immunochemically related to group II enzyme in inflammatory bowel disease: its correlation with disease activity of Crohn's disease and ulcerative colitis.

Authors:  T Minami; H Tojo; Y Shinomura; S Tarui; M Okamoto
Journal:  Gut       Date:  1992-07       Impact factor: 23.059

2.  Phospholipase A2 isoforms are altered in chronic pancreatitis.

Authors:  M Kashiwagi; H Friess; W Uhl; H Graber; R Duarte; A Zimmermann; M W Büchler
Journal:  Ann Surg       Date:  1998-02       Impact factor: 12.969

3.  Group II and IV phospholipase A(2) are produced in human pancreatic cancer cells and influence prognosis.

Authors:  M Kashiwagi; H Friess; W Uhl; P Berberat; M Abou-Shady; M Martignoni; S E Anghelacopoulos; A Zimmermann; M W Büchler
Journal:  Gut       Date:  1999-10       Impact factor: 23.059

4.  Phospholipase A2 isoforms in acute pancreatitis.

Authors:  H Friess; S Shrikhande; E Riesle; M Kashiwagi; K Baczako; A Zimmermann; W Uhl; M W Büchler
Journal:  Ann Surg       Date:  2001-02       Impact factor: 12.969

5.  Immunohistochemical localization of group II phospholipase A2 in human pancreatic carcinomas.

Authors:  H Kiyohara; H Egami; H Kako; Y Shibata; K Murata; S Ohshima; K Sei; S Suko; R Kurano; M Ogawa
Journal:  Int J Pancreatol       Date:  1993-02

6.  Splicing of a human endogenous retrovirus to a novel phospholipase A2 related gene.

Authors:  A E Feuchter-Murthy; J D Freeman; D L Mager
Journal:  Nucleic Acids Res       Date:  1993-01-11       Impact factor: 16.971

7.  Increased group II phospholipase A2 in colonic mucosa of patients with Crohn's disease and ulcerative colitis.

Authors:  T Minami; H Tojo; Y Shinomura; Y Matsuzawa; M Okamoto
Journal:  Gut       Date:  1994-11       Impact factor: 23.059

8.  Phospholipase A2 from plasma of patients with septic shock is associated with high-density lipoproteins and C3 anaphylatoxin: some implications for its functional role.

Authors:  M A Gijón; C Pérez; E Méndez; M Sánchez Crespo
Journal:  Biochem J       Date:  1995-02-15       Impact factor: 3.857

9.  Bactericidal properties of murine intestinal phospholipase A2.

Authors:  S S Harwig; L Tan; X D Qu; Y Cho; P B Eisenhauer; R I Lehrer
Journal:  J Clin Invest       Date:  1995-02       Impact factor: 14.808

10.  Quantitation of human tissue and immune cell type II 14 kDa phospholipase A(2) by enzyme immunoassay.

Authors:  B J Bolognese; S D Holmes; L J McMillan; K F Kaiser; L A Marshall
Journal:  Inflammopharmacology       Date:  1997       Impact factor: 5.093
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