Literature DB >> 27752039

Mechanisms of activation and inhibition of Zika virus NS2B-NS3 protease.

Xia Chen1,2, Kailin Yang3, Chen Wu1, Cheng Chen1, Can Hu1,2, Olga Buzovetsky4, Zefang Wang1, Xiaoyun Ji5, Yong Xiong4, Haitao Yang1,2.   

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Year:  2016        PMID： 27752039      PMCID： PMC5099865          DOI： 10.1038/cr.2016.116

Source DB:  PubMed          Journal:  Cell Res        ISSN： 1001-0602            Impact factor:   25.617


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  15 in total

1.  Zika virus genome from the Americas.

Authors:  Antoine Enfissi; John Codrington; Jimmy Roosblad; Mirdad Kazanji; Dominique Rousset
Journal:  Lancet       Date:  2016-01-08       Impact factor: 79.321

2.  Functional profiling of recombinant NS3 proteases from all four serotypes of dengue virus using tetrapeptide and octapeptide substrate libraries.

Authors:  Jun Li; Siew Pheng Lim; David Beer; Viral Patel; Daying Wen; Christine Tumanut; David C Tully; Jennifer A Williams; Jan Jiricek; John P Priestle; Jennifer L Harris; Subhash G Vasudevan
Journal:  J Biol Chem       Date:  2005-06-01       Impact factor: 5.157

Review 3.  Novel therapies for hepatitis C - one pill fits all?

Authors:  Michael P Manns; Thomas von Hahn
Journal:  Nat Rev Drug Discov       Date:  2013-06-28       Impact factor: 84.694

4.  Purified NS2B/NS3 serine protease of dengue virus type 2 exhibits cofactor NS2B dependence for cleavage of substrates with dibasic amino acids in vitro.

Authors:  R Yusof; S Clum; M Wetzel; H M Murthy; R Padmanabhan
Journal:  J Biol Chem       Date:  2000-04-07       Impact factor: 5.157

5.  Crystal structure of cat muscle pyruvate kinase at a resolution of 2.6 A.

Authors:  D I Stuart; M Levine; H Muirhead; D K Stammers
Journal:  J Mol Biol       Date:  1979-10-15       Impact factor: 5.469

6.  Anticipating the international spread of Zika virus from Brazil.

Authors:  Isaac I Bogoch; Oliver J Brady; Moritz U G Kraemer; Matthew German; Marisa I Creatore; Manisha A Kulkarni; John S Brownstein; Sumiko R Mekaru; Simon I Hay; Emily Groot; Alexander Watts; Kamran Khan
Journal:  Lancet       Date:  2016-01-15       Impact factor: 79.321

Review 7.  Zika virus: history of a newly emerging arbovirus.

Authors:  Nitwara Wikan; Duncan R Smith
Journal:  Lancet Infect Dis       Date:  2016-06-06       Impact factor: 25.071

8.  Pathology of congenital Zika syndrome in Brazil: a case series.

Authors:  Roosecelis Brasil Martines; Julu Bhatnagar; Ana Maria de Oliveira Ramos; Helaine Pompeia Freire Davi; Silvia D'Andretta Iglezias; Cristina Takami Kanamura; M Kelly Keating; Gillian Hale; Luciana Silva-Flannery; Atis Muehlenbachs; Jana Ritter; Joy Gary; Dominique Rollin; Cynthia S Goldsmith; Sarah Reagan-Steiner; Yokabed Ermias; Tadaki Suzuki; Kleber G Luz; Wanderson Kleber de Oliveira; Robert Lanciotti; Amy Lambert; Wun-Ju Shieh; Sherif R Zaki
Journal:  Lancet       Date:  2016-06-29       Impact factor: 79.321

9.  Potent cationic inhibitors of West Nile virus NS2B/NS3 protease with serum stability, cell permeability and antiviral activity.

Authors:  Martin J Stoermer; Keith J Chappell; Susann Liebscher; Christina M Jensen; Chun H Gan; Praveer K Gupta; Wei-Jun Xu; Paul R Young; David P Fairlie
Journal:  J Med Chem       Date:  2008-08-26       Impact factor: 7.446

10.  Crystal structure of Zika virus NS2B-NS3 protease in complex with a boronate inhibitor.

Authors:  Jian Lei; Guido Hansen; Christoph Nitsche; Christian D Klein; Linlin Zhang; Rolf Hilgenfeld
Journal:  Science       Date:  2016-07-07       Impact factor: 47.728
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  18 in total

Review 1.  Therapeutic Approaches for Zika Virus Infection of the Nervous System.

Authors:  Rachel P M Abrams; Jamie Solis; Avindra Nath
Journal:  Neurotherapeutics       Date:  2017-10       Impact factor: 7.620

2.  Structural insight into the Zika virus capsid encapsulating the viral genome.

Authors:  Ting Li; Qi Zhao; Xiaoyun Yang; Cheng Chen; Kailin Yang; Chen Wu; Tianqing Zhang; Yinkai Duan; Xiaoyu Xue; Kaixia Mi; Xiaoyun Ji; Zefang Wang; Haitao Yang
Journal:  Cell Res       Date:  2018-02-21       Impact factor: 25.617

3.  Jizanpeptins, Cyanobacterial Protease Inhibitors from a Symploca sp. Cyanobacterium Collected in the Red Sea.

Authors:  David A Gallegos; Josep Saurí; Ryan D Cohen; Xuemei Wan; Patrick Videau; Alec O Vallota-Eastman; Lamiaa A Shaala; Diaa T A Youssef; R Thomas Williamson; Gary E Martin; Benjamin Philmus; Aleksandra E Sikora; Jane E Ishmael; Kerry L McPhail
Journal:  J Nat Prod       Date:  2018-05-29       Impact factor: 4.050

4.  Characterization of the Zika virus two-component NS2B-NS3 protease and structure-assisted identification of allosteric small-molecule antagonists.

Authors:  Sergey A Shiryaev; Chen Farhy; Antonella Pinto; Chun-Teng Huang; Nicole Simonetti; Annie Elong Ngono; Antimone Dewing; Sujan Shresta; Anthony B Pinkerton; Piotr Cieplak; Alex Y Strongin; Alexey V Terskikh
Journal:  Antiviral Res       Date:  2017-04-29       Impact factor: 5.970

5.  Identification of novel small molecule inhibitors against NS2B/NS3 serine protease from Zika virus.

Authors:  Hyun Lee; Jinhong Ren; Salvatore Nocadello; Amy J Rice; Isabel Ojeda; Samuel Light; George Minasov; Jason Vargas; Dhanapalan Nagarathnam; Wayne F Anderson; Michael E Johnson
Journal:  Antiviral Res       Date:  2016-12-26       Impact factor: 5.970

6.  Existing drugs as broad-spectrum and potent inhibitors for Zika virus by targeting NS2B-NS3 interaction.

Authors:  Zhong Li; Matthew Brecher; Yong-Qiang Deng; Jing Zhang; Srilatha Sakamuru; Binbin Liu; Ruili Huang; Cheri A Koetzner; Christina A Allen; Susan A Jones; Haiying Chen; Na-Na Zhang; Min Tian; Fengshan Gao; Qishan Lin; Nilesh Banavali; Jia Zhou; Nathan Boles; Menghang Xia; Laura D Kramer; Cheng-Feng Qin; Hongmin Li
Journal:  Cell Res       Date:  2017-07-07       Impact factor: 25.617

Review 7.  Mosquito-Borne Flaviviruses and Current Therapeutic Advances.

Authors:  Xijing Qian; Zhongtian Qi
Journal:  Viruses       Date:  2022-06-05       Impact factor: 5.818

8.  Zika virus pathogenesis and current therapeutic advances.

Authors:  Caroline Mwaliko; Raphael Nyaruaba; Lu Zhao; Evans Atoni; Samuel Karungu; Matilu Mwau; Dimitri Lavillette; Han Xia; Zhiming Yuan
Journal:  Pathog Glob Health       Date:  2020-11-14       Impact factor: 2.894

9.  Flavonoids from Pterogyne nitens as Zika virus NS2B-NS3 protease inhibitors.

Authors:  Caroline Sprengel Lima; Melina Mottin; Leticia Ribeiro de Assis; Nathalya Cristina de Moraes Roso Mesquita; Bruna Katiele de Paula Sousa; Lais Durco Coimbra; Karina Bispo-Dos- Santos; Kimberley M Zorn; Rafael V C Guido; Sean Ekins; Rafael Elias Marques; José Luiz Proença-Modena; Glaucius Oliva; Carolina Horta Andrade; Luis Octavio Regasini
Journal:  Bioorg Chem       Date:  2021-02-11       Impact factor: 5.275

10.  Inter-organelle interactions between the ER and mitotic spindle facilitates Zika protease cleavage of human Kinesin-5 and results in mitotic defects.

Authors:  Liqiong Liu; Micquel Downs; Jesse Guidry; Edward J Wojcik
Journal:  iScience       Date:  2021-03-31
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