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Literature DB >> 27747339

A fluidic circuit based, high-efficiency and large-scale single cell trap.

Lu Mi¹, Liang Huang¹, Junxiang Li², Guoqiang Xu¹, Qiong Wu², Wenhui Wang¹.

Abstract

Single cell traps have important applications in biological cell manipulation and analysis. This paper describes a novel single cell trap design and device with a matrix of cell trap units inspired by an equivalent resistive electric circuit. This fluidic device follows the least flow resistance path principle of such devices allowing deterministic single cell trapping with high efficiency and flexibility for large scale cell patterning.

Mesh：

Year: 2016 PMID： 27747339 DOI： 10.1039/c6lc01120a

Source DB: PubMed Journal: Lab Chip ISSN： 1473-0189 Impact factor: 6.799

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Cited

11 in total

Review 1. Microfluidics cell sample preparation for analysis: Advances in efficient cell enrichment and precise single cell capture.

Authors: Liang Huang; Shengtai Bian; Yinuo Cheng; Guanya Shi; Peng Liu; Xiongying Ye; Wenhui Wang
Journal: Biomicrofluidics Date: 2017-02-06 Impact factor: 2.800

2. Transport of biomolecules to binding partners displayed on the surface of microbeads arrayed in traps in a microfluidic cell.

Authors: Xiaoxiao Chen; Thomas F Leary; Charles Maldarelli
Journal: Biomicrofluidics Date: 2017-01-04 Impact factor: 2.800

3. A novel dual-well array chip for efficiently trapping single-cell in large isolated micro-well without complicated accessory equipment.

Authors: Chenyu Wang; Wenwen Liu; Qingquan Wei; Lufeng Ren; Manqing Tan; Yude Yu
Journal: Biomicrofluidics Date: 2018-05-07 Impact factor: 2.800

A fluidic circuit based, high-efficiency and large-scale single cell trap.

Review 1. Microfluidics cell sample preparation for analysis: Advances in efficient cell enrichment and precise single cell capture.

2. Transport of biomolecules to binding partners displayed on the surface of microbeads arrayed in traps in a microfluidic cell.

3. A novel dual-well array chip for efficiently trapping single-cell in large isolated micro-well without complicated accessory equipment.

4. On-chip cell labelling and washing by capture and release using microfluidic trap arrays.

Review 5. Single-cell patterning technology for biological applications.

Review 6. Microfluidic systems for hydrodynamic trapping of cells and clusters.

7. A passive Stokes flow rectifier for Newtonian fluids.

Review 8. Microfluidic Single-Cell Manipulation and Analysis: Methods and Applications.

9. An acoustofluidic trap and transfer approach for organizing a high density single cell array.

10. Time Sequential Single-Cell Patterning with High Efficiency and High Density.