Literature DB >> 27747258

Using Cognitive Interviews to Enhance Measurement in Empirical Bioethics: Developing a Measure of the Preventive Misconception in Biomedical HIV Prevention Trials.

Jeremy Sugarman1, Damon M Seils2, J Kemp Watson-Ormond2, Kevin P Weinfurt3.   

Abstract

BACKGROUND: We describe our use of cognitive interviews in developing a measure of "preventive misconception" to demonstrate the importance of this approach to researchers developing surveys in empirical bioethics. The preventive misconception involves research participants' false beliefs about a prevention trial, including beliefs that the interventions being tested will certainly be effective.
METHODS: We developed and refined a measure of the preventive misconception using qualitative interviews that focused on cognitive testing of proposed survey items with HIV prevention trial participants.
RESULTS: Two main problems emerged during initial interviews. First, the phrase "reduce your risk," used to elicit beliefs about risk reduction from the use of study medications, was interpreted as relating to a reduction of risky behaviors. Second, the phrase "participating in this study," intended to elicit beliefs about trial group assignment, was interpreted as relating to personal behavior changes associated with study participation. Additional interviews using a revised measure were no longer problematic in these ways, and participants felt the response options were appropriate for conveying their answers.
CONCLUSIONS: These findings underscore the importance of cognitive testing in developing surveys for empirical bioethics.

Entities:  

Keywords:  Bioethics; Empirical Research; HIV/AIDS; Health Risk Behaviors; Interview; Qualitative Research

Mesh:

Year:  2015        PMID: 27747258      PMCID: PMC5063236          DOI: 10.1080/23294515.2015.1037967

Source DB:  PubMed          Journal:  AJOB Empir Bioeth        ISSN: 2329-4515


  11 in total

1.  Developing model language for disclosing financial interests to potential clinical research participants.

Authors:  Kevin P Weinfurt; Jennifer S Allsbrook; Joëlle Y Friedman; Michaela A Dinan; Mark A Hall; Kevin A Schulman; Jeremy Sugarman
Journal:  IRB       Date:  2007 Jan-Feb

2.  Preventive misconception: its nature, presence, and ethical implications for research.

Authors:  Alan E Simon; Albert W Wu; Philip W Lavori; Jeremy Sugarman
Journal:  Am J Prev Med       Date:  2007-05       Impact factor: 5.043

3.  Cognitive interviewing as a tool for improving the informed consent process.

Authors:  Gordon Willis
Journal:  J Empir Res Hum Res Ethics       Date:  2006-03       Impact factor: 1.742

4.  Quality of informed consent: a new measure of understanding among research subjects.

Authors:  S Joffe; E F Cook; P D Cleary; J W Clark; J C Weeks
Journal:  J Natl Cancer Inst       Date:  2001-01-17       Impact factor: 13.506

5.  Preventive misconception as a motivation for participation and adherence in microbicide trials: evidence from female participants and male partners in Malawi and Zimbabwe.

Authors:  Cynthia Woodsong; Patty Alleman; Petina Musara; Adlight Chandipwisa; Mike Chirenje; Francis Martinson; Irving Hoffman
Journal:  AIDS Behav       Date:  2012-04

6.  Preventive misconception and adolescents' knowledge about HIV vaccine trials.

Authors:  Mary A Ott; Andreia B Alexander; Michelle Lally; John B Steever; Gregory D Zimet
Journal:  J Med Ethics       Date:  2013-01-25       Impact factor: 2.903

7.  Evaluation of item candidates: the PROMIS qualitative item review.

Authors:  Darren A DeWalt; Nan Rothrock; Susan Yount; Arthur A Stone
Journal:  Med Care       Date:  2007-05       Impact factor: 2.983

8.  Informed consent for biorepositories: assessing prospective participants' understanding and opinions.

Authors:  Laura M Beskow; Elizabeth Dean
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2008-06       Impact factor: 4.254

9.  "If It's Not Working, Why Would They Be Testing It?": mental models of HIV vaccine trials and preventive misconception among men who have sex with men in India.

Authors:  Venkatesan Chakrapani; Peter A Newman; Neeti Singhal; Ruban Nelson; Murali Shunmugam
Journal:  BMC Public Health       Date:  2013-08-07       Impact factor: 3.295

10.  Willingness to participate in HIV vaccine trials among men who have sex with men in Chennai and Mumbai, India: a social ecological approach.

Authors:  Venkatesan Chakrapani; Peter A Newman; Neeti Singhal; Jhalak Jerajani; Murali Shunmugam
Journal:  PLoS One       Date:  2012-12-04       Impact factor: 3.240

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  4 in total

1.  Willingness to Donate Organs Among People Living With HIV.

Authors:  Anh Q Nguyen; Saad K Anjum; Samantha E Halpern; Komal Kumar; Sarah E Van Pilsum Rasmussen; Brianna Doby; Ashton A Shaffer; Allan B Massie; Aaron A R Tobian; Dorry L Segev; Jeremy Sugarman; Christine M Durand
Journal:  J Acquir Immune Defic Syndr       Date:  2018-09-01       Impact factor: 3.731

2.  Preventive Misconception and Risk Behaviors in a Multinational HIV Prevention Trial.

Authors:  Jeremy Sugarman; Li Lin; Jared M Baeten; Thesla Palanee-Phillips; Elizabeth R Brown; Flavia Matovu Kiweewa; Nyaradzo M Mgodi; Gonasagrie Nair; Samantha Siva; Damon M Seils; Kevin P Weinfurt
Journal:  AJOB Empir Bioeth       Date:  2019-04-19

3.  Brief Report: Willingness to Accept HIV-Infected and Increased Infectious Risk Donor Organs Among Transplant Candidates Living With HIV.

Authors:  Shanti M Seaman; Sarah E Van Pilsum Rasmussen; Anh Q Nguyen; Samantha E Halpern; Susan You; Madeleine M Waldram; Saad K Anjum; Mary Grace Bowring; Abimereki D Muzaale; Darin B Ostrander; Diane Brown; Allan B Massie; Aaron A R Tobian; Macey L Henderson; Faith E Fletcher; Burke Smith; Ada Chao; Nishita Gorupati; Katya Prakash; Saima Aslam; Dong H Lee; Varvara Kirchner; Timothy L Pruett; Ghady Haidar; Kailey Hughes; Maricar Malinis; Sonya Trinh; Dorry L Segev; Jeremy Sugarman; Christine M Durand
Journal:  J Acquir Immune Defic Syndr       Date:  2020-09-01       Impact factor: 3.771

4.  Facilitators of adherence to the study pill in the FEM-PrEP clinical trial.

Authors:  Amy Corneli; Brian Perry; Kawango Agot; Khatija Ahmed; Fulufhelo Malamatsho; Lut Van Damme
Journal:  PLoS One       Date:  2015-04-13       Impact factor: 3.240

  4 in total

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