Literature DB >> 27747027

Developing miRNA therapeutics for cardiac repair in ischemic heart disease.

Kai Zhu1, Dingqian Liu1, Hao Lai1, Jun Li1, Chunsheng Wang1.   

Abstract

MicroRNAs (miRNAs) families have been found to be powerful regulators in a wide variety of diseases, which enables the possible use of miRNAs in therapeutic strategies for cardiac repair after ischemic heart disease. This review provides some general insights into miRNAs modulation for development of current molecular and cellular therapeutics in cardiac repair, including endogenous regeneration, endogenous repair, stem cells transplantation, and reprogramming. We also review the delivery strategies for miRNAs modulation, and briefly summarize the current bench and clinical efforts that are being made to explore miRNAs as the future therapeutic target.

Entities:  

Keywords:  MicroRNAs (miRNAs); cardiac repair; modulation; regeneration; stem cells

Year:  2016        PMID： 27747027      PMCID： PMC5059336          DOI： 10.21037/jtd.2016.08.93

Source DB:  PubMed          Journal:  J Thorac Dis        ISSN： 2072-1439            Impact factor:   2.895


  76 in total

Review 1.  Challenges in using stem cells for cardiac repair.

Authors:  Christine L Mummery; Richard P Davis; Jose E Krieger
Journal:  Sci Transl Med       Date:  2010-04-14       Impact factor: 17.956

2.  MicroRNA-101 inhibited postinfarct cardiac fibrosis and improved left ventricular compliance via the FBJ osteosarcoma oncogene/transforming growth factor-β1 pathway.

Authors:  Zhenwei Pan; Xuelin Sun; Hongli Shan; Ning Wang; Jinghao Wang; Jinshuai Ren; Shuya Feng; Liangjun Xie; Chunying Lu; Ye Yuan; Yang Zhang; Ying Wang; Yanjie Lu; Baofeng Yang
Journal:  Circulation       Date:  2012-07-18       Impact factor: 29.690

3.  AngiomiR-126 expression and secretion from circulating CD34(+) and CD14(+) PBMCs: role for proangiogenic effects and alterations in type 2 diabetics.

Authors:  Pavani Mocharla; Sylvie Briand; Giovanna Giannotti; Carola Dörries; Philipp Jakob; Francesco Paneni; Thomas Lüscher; Ulf Landmesser
Journal:  Blood       Date:  2012-11-08       Impact factor: 22.113

Review 4.  Progress in microRNA delivery.

Authors:  Yu Zhang; Zaijie Wang; Richard A Gemeinhart
Journal:  J Control Release       Date:  2013-09-25       Impact factor: 9.776

5.  Inhibitory effect of hsa-miR-590-5p on cardiosphere-derived stem cells differentiation through downregulation of TGFB signaling.

Authors:  Samaneh Ekhteraei-Tousi; Bahram Mohammad-Soltani; Majid Sadeghizadeh; Seyed Javad Mowla; Sepideh Parsi; Masoud Soleimani
Journal:  J Cell Biochem       Date:  2015-01       Impact factor: 4.429

Review 6.  Cell therapy for cardiac repair--lessons from clinical trials.

Authors:  Atta Behfar; Ruben Crespo-Diaz; Andre Terzic; Bernard J Gersh
Journal:  Nat Rev Cardiol       Date:  2014-03-04       Impact factor: 32.419

7.  MicroRNA-92a controls angiogenesis and functional recovery of ischemic tissues in mice.

Authors:  Angelika Bonauer; Guillaume Carmona; Masayoshi Iwasaki; Marina Mione; Masamichi Koyanagi; Ariane Fischer; Jana Burchfield; Henrik Fox; Carmen Doebele; Kisho Ohtani; Emmanouil Chavakis; Michael Potente; Marc Tjwa; Carmen Urbich; Andreas M Zeiher; Stefanie Dimmeler
Journal:  Science       Date:  2009-05-21       Impact factor: 47.728

Review 8.  MicroRNAs: key regulators of stem cells.

Authors:  Vamsi K Gangaraju; Haifan Lin
Journal:  Nat Rev Mol Cell Biol       Date:  2009-02       Impact factor: 94.444

9.  MicroRNA-155 prevents necrotic cell death in human cardiomyocyte progenitor cells via targeting RIP1.

Authors:  Jia Liu; Alain van Mil; Krijn Vrijsen; Jiajun Zhao; Ling Gao; Corina H G Metz; Marie-José Goumans; Pieter A Doevendans; Joost P G Sluijter
Journal:  J Cell Mol Med       Date:  2010-06-09       Impact factor: 5.310

10.  MicroRNA-363 negatively regulates the left ventricular determining transcription factor HAND1 in human embryonic stem cell-derived cardiomyocytes.

Authors:  Vilas Wagh; Alexander Pomorski; Karlijn J Wilschut; Sebastian Piombo; Harold S Bernstein
Journal:  Stem Cell Res Ther       Date:  2014-06-06       Impact factor: 6.832
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  13 in total

1.  Targeting miRNA for Therapy of Juvenile and Adult Diabetic Cardiomyopathy.

Authors:  Shyam Sundar Nandi; Paras Kumar Mishra
Journal:  Adv Exp Med Biol       Date:  2018       Impact factor: 2.622

Review 2.  Autologous Bone Marrow-Derived Stem Cells for Treating Diabetic Neuropathy in Metabolic Syndrome.

Authors:  Wei Liu; Fengchun Yu; Zhenghong Zhou; Yi-Chen Li; Dongsheng Fan; Kai Zhu
Journal:  Biomed Res Int       Date:  2017-10-01       Impact factor: 3.411

3.  Function and mechanism of microRNA-210 in acute cerebral infarction.

Authors:  Jun Wang; Yuezhan Zhang; Feng Xu
Journal:  Exp Ther Med       Date:  2017-11-27       Impact factor: 2.447

4.  mi R -15a/15b Cluster Modulates Survival of Mesenchymal Stem Cells to Improve Its Therapeutic Efficacy of Myocardial Infarction.

Authors:  Yingfeng Tu; Yan Qiu; Li Liu; Tao Huang; Hao Tang; Youbin Liu; Wenguang Guo; Hongchi Jiang; Yuhua Fan; Bo Yu
Journal:  J Am Heart Assoc       Date:  2019-01-08       Impact factor: 5.501

5.  Effect of HIF-1α/miR-10b-5p/PTEN on Hypoxia-Induced Cardiomyocyte Apoptosis.

Authors:  Liping Wu; Yafen Chen; Yuanyuan Chen; Wenbo Yang; Yanxin Han; Lin Lu; Ke Yang; Jiumei Cao
Journal:  J Am Heart Assoc       Date:  2019-09-04       Impact factor: 5.501

6.  Role of MicroRNA-34a in Anti-Apoptotic Effects of Granulocyte-Colony Stimulating Factor in Diabetic Cardiomyopathy.

Authors:  In Hwa Park; Yi Sun Song; Hyun Woo Joo; Guang Yin Shen; Jin Hee Seong; Na Kyoung Shin; Young Jong Cho; Yonggu Lee; Jeong Hun Shin; Young Hyo Lim; Hyuck Kim; Kyung Soo Kim
Journal:  Diabetes Metab J       Date:  2019-04-23       Impact factor: 5.376

7.  MicroRNA-29b alleviates oxygen and glucose deprivation/reperfusion-induced injury via inhibition of the p53-dependent apoptosis pathway in N2a neuroblastoma cells.

Authors:  Lei Cao; Yu Zhang; Shuai Zhang; Tian-Peng Jiang; Li Chen; Jing Liu; Shi Zhou
Journal:  Exp Ther Med       Date:  2017-10-31       Impact factor: 2.447

8.  MicroRNA-23a/27a/24-2 cluster promotes gastric cancer cell proliferation synergistically.

Authors:  Kate Hua; Yu-Ting Chen; Chian-Feng Chen; Ya-Syuan Tang; Tzu-Ting Huang; Yu-Cheng Lin; Tien-Shun Yeh; Kuo-Hung Huang; Hsin-Chen Lee; Ming-Ta Hsu; Chin-Wen Chi; Chew-Wun Wu; Chi-Hung Lin; Yueh-Hsin Ping
Journal:  Oncol Lett       Date:  2018-06-07       Impact factor: 2.967

9.  Development of microRNA-21 mimic nanocarriers for the treatment of cutaneous wounds.

Authors:  Sun Young Wang; Hyosuk Kim; Gijung Kwak; Sung Duk Jo; Daeho Cho; Yoosoo Yang; Ick Chan Kwon; Ji Hoon Jeong; Sun Hwa Kim
Journal:  Theranostics       Date:  2020-02-10       Impact factor: 11.556

Review 10.  Editorial focus: understanding off-target effects as the key to successful RNAi therapy.

Authors:  Rafal Bartoszewski; Aleksander F Sikorski
Journal:  Cell Mol Biol Lett       Date:  2019-12-09       Impact factor: 5.787
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