Literature DB >> 27746417

A review of complementary therapies for chemotherapy induced gastrointestinal mucositis.

Raja A H Kuchay1.   

Abstract

Administration of chemotherapy often leads to gastrointestinal mucositis (GIM). GIM manifests as nausea, abdominal pain and diarrhoea in recipients of chemotherapy. GIM is a major complication occurring in approximately 80% of patients receiving 5-flurouracil treatment. These side-effects may become so severe that significant dose reductions are required, ultimately affecting treatment efficacy and patient survival. Complementary and alternative medicine (CAM) is a growing area of public interest. This review will provide an overview of current knowledge of complementary medicinal therapies for chemotherapy induced GIM. An understanding of this evolving literature is useful in discussing these therapies with patients who are considering using them.

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Year:  2016        PMID: 27746417     DOI: 10.5582/ddt.2016.01059

Source DB:  PubMed          Journal:  Drug Discov Ther        ISSN: 1881-7831


  1 in total

1.  Activation of G protein coupled estrogen receptor prevents chemotherapy-induced intestinal mucositis by inhibiting the DNA damage in crypt cell in an extracellular signal-regulated kinase 1- and 2- dependent manner.

Authors:  Guanyu Chen; Honghui Zeng; Xinyun Li; Jianbo Liu; Zhao Li; Runze Xu; Yuntao Ma; Chuanyong Liu; Bing Xue
Journal:  Cell Death Dis       Date:  2021-10-30       Impact factor: 8.469

  1 in total

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