| Literature DB >> 27746100 |
Zhihui Xu1, Xueyan Shi2, Huijun Jiang2, Yiyan Song1, Liying Zhang2, Fangyuan Wang2, Shuhu Du2, Jin Chen3.
Abstract
We developed a method to regenerate arrayed gold microelectrodes equipped for a commercial label-free cell analyzer. The regeneration process includes efficient treatment of the gold surface with trypsin (0.25%, v/v) digestion, rinsing with ethanol and deionized water and spinning steps. The proposed method ensured complete regeneration and repeated usage of gold microchips up to 4 times for the real-time electric impedance measurement of anti-cancer drug cytotoxicity.Entities:
Keywords: Arrayed gold microelectrodes; Drug cytotoxicity; Real-time cell analyzer; Regeneration; Trypsin-digestion
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Year: 2016 PMID： 27746100 DOI： 10.1016/j.ab.2016.10.012
Source DB: PubMed Journal: Anal Biochem ISSN： 0003-2697 Impact factor: 3.365