BACKGROUND: The aim of this study is to assess the effect of body mass index (BMI) on outcomes of in vitro fertilization (IVF) / intracytoplasmic sperm injection (ICSI) among polycystic ovarian syndrome (PCOS) and non-PCOS patients. METHODS: This was a retrospective cohort study that was performed in the Second Hospital of Hebei Medical University. Patients who were under 35 years old were included in the study and were divided into four groups based on their BMI. The number of retrieved oocytes, implantation rate, clinical pregnancy rate, miscarriage rate and live births among PCOS and non-PCOS patients were compared between different BMIs. RESULTS: IVF/ICSI pregnancies in obese PCOS women had a considerably higher risk of miscarriage and low rate of clinical pregnancy than in non-obese PCOS pregnancies. However, in non-PCOS patient, obesity significantly elevated miscarriage rate but did not affect clinical pregnancy rate. CONCLUSION: Obesity in PCOS patients led to poor outcomes of IVF/ICSI.
BACKGROUND: The aim of this study is to assess the effect of body mass index (BMI) on outcomes of in vitro fertilization (IVF) / intracytoplasmic sperm injection (ICSI) among polycystic ovarian syndrome (PCOS) and non-PCOSpatients. METHODS: This was a retrospective cohort study that was performed in the Second Hospital of Hebei Medical University. Patients who were under 35 years old were included in the study and were divided into four groups based on their BMI. The number of retrieved oocytes, implantation rate, clinical pregnancy rate, miscarriage rate and live births among PCOS and non-PCOSpatients were compared between different BMIs. RESULTS:IVF/ICSI pregnancies in obese PCOSwomen had a considerably higher risk of miscarriage and low rate of clinical pregnancy than in non-obese PCOS pregnancies. However, in non-PCOSpatient, obesity significantly elevated miscarriage rate but did not affect clinical pregnancy rate. CONCLUSION:Obesity in PCOSpatients led to poor outcomes of IVF/ICSI.
Authors: Rashmi Kudesia; Hongyu Wu; Karen Hunter Cohn; Lei Tan; Joseph A Lee; Alan B Copperman; Piraye Yurttas Beim Journal: J Assist Reprod Genet Date: 2018-08-21 Impact factor: 3.412
Authors: Szu-Ting Yang; Chia-Hao Liu; Sheng-Hsiang Ma; Wen-Hsun Chang; Yi-Jen Chen; Wen-Ling Lee; Peng-Hui Wang Journal: Int J Environ Res Public Health Date: 2022-07-26 Impact factor: 4.614
Authors: Maisoon D Yousif; Michele D Calder; Jin Tong Du; Kelsey N Ruetz; Kylie Crocker; Brad L Urquhart; Dean H Betts; Basim Abu Rafea; Andrew J Watson Journal: Reprod Sci Date: 2020-06-15 Impact factor: 3.060