| Literature DB >> 27743075 |
J P Courpied1, P Deplus1, J Barthas1, M Forest2, A Carlioz2, M C Vacher-Lavenu2, J Crouzette3, P Fournier4, M Baufume4.
Abstract
The tolerance and response of bone to bioglass have been studied using implants of various chemical constitution in animals.Glass discs were inserted between the inner and outer tables of the skull in 32 rabbits and small glass stick were implanted in the medullary cavity of long bones in 6 dogs. The results were analysed between 6 and 18 months later. High resolution radiographs and histopathological examination were performed.Some glass behaves like an inert material but other specimens are biodegradable and induce a satisfactory bone response in adjacent bone. Any new bone formation does not follow the classical stages of connective tissue, cartilage and woven bone. Bioglass is more suitable for bone than many other materials now in use and further applications in orthopaedic surgery may be considered.Entities:
Keywords: Bioglass; Biomaterials; Bone; Implant; Osteogenesis
Year: 1982 PMID: 27743075 DOI: 10.1007/BF00267809
Source DB: PubMed Journal: Int Orthop ISSN: 0341-2695 Impact factor: 3.075