Literature DB >> 27741965

Pharmacotherapies in Geriatric Chronic Pain Management.

Zachary A Marcum1, Nakia A Duncan2, Una E Makris3.   

Abstract

Pharmacologic management of chronic pain in older adults is one component of the multimodal, interdisciplinary management of this complex condition. In this article, we summarize several of the key barriers to effective pharmacologic management in older adults and review the existing (albeit limited) evidence for its effectiveness and safety, especially in a medically complex population with multimorbidity. This review covers topical formulations, acetaminophen, oral nonsteroidal antiinflammatory drugs, and adjuvant therapies. The article concludes with a suggested approach to managing chronic pain in the older patient, incorporating goals and expectations for treatment as well as careful monitoring of medication adjustments. Published by Elsevier Inc.

Entities:  

Keywords:  Adverse drug events; Chronic pain; Medication; Older adults; Polypharmacy

Mesh：

Substances：

Year:  2016        PMID： 27741965      PMCID： PMC5123672          DOI： 10.1016/j.cger.2016.06.007

Source DB:  PubMed          Journal:  Clin Geriatr Med        ISSN： 0749-0690            Impact factor:   3.076


  80 in total

Review 1.  The management of persistent pain in older persons.

Authors: 
Journal:  J Am Geriatr Soc       Date:  2002-06       Impact factor: 5.562

2.  American Geriatrics Society 2015 Updated Beers Criteria for Potentially Inappropriate Medication Use in Older Adults.

Authors: 
Journal:  J Am Geriatr Soc       Date:  2015-10-08       Impact factor: 5.562

3.  Consideration of multiple chronic diseases in randomized controlled trials.

Authors:  Alejandro R Jadad; Matthew J To; Mohamed Emara; Jennifer Jones
Journal:  JAMA       Date:  2011-12-28       Impact factor: 56.272

Review 4.  Venlafaxine for neuropathic pain in adults.

Authors:  Helen C Gallagher; Ruth M Gallagher; Michelle Butler; Donal J Buggy; Martin C Henman
Journal:  Cochrane Database Syst Rev       Date:  2015-08-23

5.  Considerations for the appropriate use of skeletal muscle relaxants for the management of acute low back pain.

Authors:  Corey Witenko; Robin Moorman-Li; Carol Motycka; Kevin Duane; Juan Hincapie-Castillo; Paul Leonard; Christopher Valaer
Journal:  P T       Date:  2014-06

6.  [U.S. Food and Drug Administration (FDA) strengthens warning that non-aspirin non steroidal anti-inflammatory drugs (NSAIDs) can cause myocardial infarctions or strokes: the dentist's perspective].

Authors:  E Rosen; I Tsesis; M Vered
Journal:  Refuat Hapeh Vehashinayim (1993)       Date:  2015-10

7.  The effect of either topical menthol or a placebo on functioning and knee pain among patients with knee OA.

Authors:  Robert Topp; Joseph A Brosky; David Pieschel
Journal:  J Geriatr Phys Ther       Date:  2013 Apr-Jun       Impact factor: 3.381

8.  Informed choice and the widespread use of antiinflammatory drugs.

Authors:  Liana Fraenkel; Dick R Wittink; John Concato; Terri Fried
Journal:  Arthritis Rheum       Date:  2004-04-15

9.  NSAIDs and the gastrointestinal tract.

Authors:  Maneesh Gupta; Glenn M Eisen
Journal:  Curr Gastroenterol Rep       Date:  2009-10

Review 10.  Cardiovascular risk with non-steroidal anti-inflammatory drugs: systematic review of population-based controlled observational studies.

Authors:  Patricia McGettigan; David Henry
Journal:  PLoS Med       Date:  2011-09-27       Impact factor: 11.069
View more
  11 in total

1.  Population pharmacokinetic modelling of intravenous paracetamol in fit older people displays extensive unexplained variability.

Authors:  P Mian; M J van Esdonk; K T Olkkola; B C M de Winter; A Liukas; I Spriet; D Tibboel; M Petrovic; B C P Koch; K Allegaert
Journal:  Br J Clin Pharmacol       Date:  2018-10-25       Impact factor: 4.335

2.  Highly Variable Paracetamol Pharmacokinetics After Multiple Oral Dosing in Frail Older People: A Population Pharmacokinetic Analysis.

Authors:  L T van der Heijden; P Mian; J Hias; B C M de Winter; J Tournoy; L Van der Linden; D Tibboel; K Walgraeve; J Flamaing; B C P Koch; K Allegaert; I Spriet
Journal:  Drugs Aging       Date:  2021-12-17       Impact factor: 3.923

Review 3.  Diagnosis and Management of Pain in Parkinson's Disease: A New Approach.

Authors:  Veit Mylius; Jens Carsten Möller; Stephan Bohlhalter; Daniel Ciampi de Andrade; Santiago Perez Lloret
Journal:  Drugs Aging       Date:  2021-07-05       Impact factor: 3.923

Review 4.  Musculoskeletal Pain in Older Adults: A Clinical Review.

Authors:  Travis P Welsh; Ailing E Yang; Una E Makris
Journal:  Med Clin North Am       Date:  2020-07-15       Impact factor: 5.456

5.  Back pain and heart failure in community-dwelling older adults: Findings from the Health ABC study.

Authors:  Jie Chen; Yiming Zhang; Eleanor Simonsick; Angela Starkweather; Ming-Hui Chen; Paula McCauley; Deborah Chyun; Xiaomei Cong
Journal:  Geriatr Nurs       Date:  2021-04-03       Impact factor: 2.361

6.  Formulation, validation and evaluation studies on metaxalone and diclofenac potassium topical gel.

Authors:  Ashutosh Tiwari; Puja Bag; Mrinmoy Sarkar; Viney Chawla; Pooja A Chawla
Journal:  Environ Anal Health Toxicol       Date:  2021-01-11

Review 7.  Paracetamol in Older People: Towards Evidence-Based Dosing?

Authors:  Paola Mian; Karel Allegaert; Isabel Spriet; Dick Tibboel; Mirko Petrovic
Journal:  Drugs Aging       Date:  2018-07       Impact factor: 3.923

8.  Pain and Inflammation Management in Older Adults: A Brazilian Consensus of Potentially Inappropriate Medication and Their Alternative Therapies.

Authors:  Fabiane Raquel Motter; Sarah Nicole Hilmer; Vera Maria Vieira Paniz
Journal:  Front Pharmacol       Date:  2019-12-02       Impact factor: 5.810

9.  Deficits in pain medication in older adults with chronic pain receiving home care: A cross-sectional study in Germany.

Authors:  Juliana Schneider; Engi Algharably; Andrea Budnick; Arlett Wenzel; Dagmar Dräger; Reinhold Kreutz
Journal:  PLoS One       Date:  2020-02-21       Impact factor: 3.240

10.  The Risk of Drug-Drug Interactions with Paracetamol in a Population of Hospitalized Geriatric Patients.

Authors:  Lykke Ida Kaas Oldenburg; Kim Peder Dalhoff; Luana Østerdal Sandoval; Charlotte Vermehren
Journal:  J Pharm (Cairo)       Date:  2020-01-19
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.